APP, amyloid beta precursor protein, 351

N. diseases: 485; N. variants: 114
Disease: Hypothalamic Dysfunction Syndromes ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751230
Disease: Hypothalamic Dysfunction Syndromes
Hypothalamic Dysfunction Syndromes 		0.010 Biomarker disease BEFREE Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neurons. 24990930 2014