KLK1, kallikrein 1, 3816

N. diseases: 132; N. variants: 3
Disease: Diabetic Nephropathy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.310 AlteredExpression disease BEFREE Since the kallikrein-kinin system (KKS) has been linked to cellular inflammatory process in many diseases, it is likely that KLK1 expression may mediate the inflammatory process during the development of diabetic nephropathy. 24586431 2014
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.310 Therapeutic disease CTD_human Here, we determined the role of the kallikrein-kinin system in the pathogenesis of streptozotocin-induced diabetic nephropathy in wild-type and tissue kallikrein-knockout mice. 19516248 2009