KRAS, KRAS proto-oncogene, GTPase, 3845

N. diseases: 1213; N. variants: 54
Disease: Low grade serous carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3839184
Disease: Low grade serous carcinoma
Low grade serous carcinoma 		0.050 GeneticVariation disease BEFREE CAISMOV24 cell line harbored KRAS mutation with wild type TP53, therefore it is characterized as low-grade serous carcinoma. 29132324 2017
CUI: C3839184
Disease: Low grade serous carcinoma
Low grade serous carcinoma 		0.050 GeneticVariation disease BEFREE The present study indicated a low frequency of BRAF or KRAS mutation in Chinese patients with LGSC of the ovary, and neither KRAS nor BRAF mutation is a prognostic factor. 29273082 2017
CUI: C3839184
Disease: Low grade serous carcinoma
Low grade serous carcinoma 		0.050 GeneticVariation disease BEFREE In this study, we correlated the morphologic and immunohistochemical phenotypes of 71 APSTs and 18 LGSCs with the mutational status of KRAS and BRAF, the most common molecular genetic changes in these neoplasms. 25188864 2014
CUI: C3839184
Disease: Low grade serous carcinoma
Low grade serous carcinoma 		0.050 GeneticVariation disease BEFREE KRAS and BRAF mutations are common in LGSC, leading to clinical trials targeting the MAPK pathway. 25523272 2014
CUI: C3839184
Disease: Low grade serous carcinoma
Low grade serous carcinoma 		0.050 GeneticVariation disease BEFREE KRAS (but not BRAF) mutations in ovarian serous borderline tumour are associated with recurrent low-grade serous carcinoma. 24549645 2013