LEP, leptin, 3952

N. diseases: 114; N. variants: 3
Disease: Steatohepatitis ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.400 Biomarker disease CTD_human In vivo cytochrome P450 activity alterations in diabetic nonalcoholic steatohepatitis mice. 27712037 2017
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.400 Biomarker disease CTD_human Stevia-derived compounds attenuate the toxic effects of ectopic lipid accumulation in the liver of obese mice: a transcriptomic and metabolomic study. 25554529 2015
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.400 Biomarker disease CTD_human Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21. 23839791 2014
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.400 Biomarker disease CTD_human Chronic exposure to low doses of pharmaceuticals disturbs the hepatic expression of circadian genes in lean and obese mice. 24525044 2014
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.400 Biomarker disease CTD_human A small molecule that blocks fat synthesis by inhibiting the activation of SREBP. 19716478 2009
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.400 Biomarker disease CTD_human Leptin may play a role in tamoxifen-induced hepatic steatosis. 12661780 2003