Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In a previous work, we showed that in TNBC miR-210 is expressed in tumor cells and also in the tumor microenvironment (TME), particularly in inflammatory CD45-LCA positive cells.
|
31787032 |
2020 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
However, by increasing the patient number from the big data analysis, miR-210 as well as miR-382 expression in tumor tissues was significantly higher than the normal tissues.
|
31596872 |
2019 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The expression of miR-210, miR-21 and miR-126 was performed using qRT-PCR in adenocarcinoma (no = 35), adenomas (no = 51), and neoplasm free controls (no = 101).
|
30357530 |
2019 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In this pilot study, low serum miR-210 expression levels and large primary tumors were identified to be markers of PPGL malignancy on univariable analysis.
|
31146085 |
2019 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Moreover, MYCBP expression was positively correlated with tumor volume, and metastasis was associated with the expression of miR-210-5p and TGF-α in our patient cohort.
|
30951707 |
2019 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Uptake of the complex in GBM cells induced the levels of miR210 targeted tumor suppressor genes, NeuroD2 and HIF3A.
|
31726199 |
2019 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Taken together, these results suggest that miR‑210‑3p may act as a tumor suppressor in ovarian cancer cells and affect the sensitivity of cells to cisplatin by directly targeting E2F3.
|
30957179 |
2019 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In lung specimens (tumor and non-tumor), microRNAs known to be involved in lung tumorigenesis (miR-21, miR-200b, miR-126, miR-451, miR-210, miR-let7c, miR-30a-30p, miR-155 and miR-let7a, qRT-PCR), DNA methylation, and downstream biomarkers were determined (qRT-PCR and immunoblotting) in 40 patients with LC (prospective study, subdivided into LC-COPD and LC, <i>N</i> = 20/group).
|
29371906 |
2018 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The effect of miR-210-3p in vivo was investigated with a tumor xenograft model in mice.
|
29445446 |
2018 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In addition, the tumor displayed a pseudohypoxic phenotype consisting in overexpression of the hypoxia-inducible factor (HIF)-1α and miR-210, as well as downregulation of the iron-sulfur cluster assembly enzyme (ISCU) involved in SDHB maturation.
|
29126304 |
2018 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In conclusion, Serum exosomal miR-210 originating from tumor tissue has potential as a novel noninvasive biomarker for the detection and prognosis of ccRCC.
|
30304555 |
2018 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
miR-210 was significantly higher in N1 PCa compared with nonmetastatic PCa, whereas the metastatic tumor revealed a lower expression level of miR-210 than the primary tumor.
|
30109809 |
2018 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In conclusion, the findings of the present study suggested that miR-210 exerted tumor carcinogenic functions in osteosarcoma by targeting FGFRL1.
|
30008923 |
2018 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The expression of miR-210 was negatively correlated with TNM stage and tumor size of pancreatic cancer.
|
30575904 |
2018 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
A PCR array identified miRNA biomarkers of solid RCC tumors (miR-210, MiR-34a, miR-155-5p and miR-150-5p) that were increased by 2-8 fold in 786-O exosomes compared with the control.
|
30061948 |
2018 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Likewise, microRNA-210 transfection nearly totally inhibited tumor xenograft growth, proliferation and metastasis without obvious side effects in vivo.
|
27940128 |
2017 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Analysis of correlations between MiR-210 expression with clinical features such as age, sex, disease type, COPD disease classification, pathological pattern of neoplasia and TNM staging.
|
28745794 |
2017 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
MiR-210 is overexpressed in UTUC compared to non-cancerous urothelium (<i>p</i> < 0.001); it is also upregulated in high-stage and high-grade tumors (<i>p</i> = 0.020 and 0.049, respectively).
|
28638274 |
2017 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
These results were corroborated by in vivo xenograft studies, which showed enhanced growth of tumors from miR-210-3p-depleted A498 cells.
|
28152509 |
2017 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
However, the role of miR-210 in the pathogenesis of SDH-related tumors remains an unmet challenge.
|
28036268 |
2017 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Thus, miR-210 could be a potential marker for judging tumor malignancy and be taken as an effective target for clinical auxiliary treatment of neurilemmoma.
|
28440459 |
2017 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Taken together, our results demonstrate that miR-210 is expressed in tumor cells but also in the tumor microenvironment.
|
28402752 |
2017 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
MiR-210-3p inhibits the tumor growth and metastasis of bladder cancer via targeting fibroblast growth factor receptor-like 1.
|
28861329 |
2017 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Recent studies have provided a wealth of evidence that miRNAs are significant members of the adaptive response to low oxygen in tumors. miR-210 is one of the hypoxia-induced miRNAs, which has been reported extensively in cancer researches.
|
28317401 |
2017 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Among them, miR-18a and miR-210 were validated in the second CUB set, showing significantly higher expression in tumor and CUBs than in reduction mammoplasty controls.
|
27789587 |
2017 |