MDM4, MDM4 regulator of p53, 4194

N. diseases: 20; N. variants: 4
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.600 Biomarker disease CTD_human In summary, HDMX exhibits bona fide oncogenic properties and offers a promising molecular target for GBM therapeutic intervention. 20472715 2010
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.600 GenomicAlterations disease CGI
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.500 Biomarker disease CTD_human Genome-wide association studies identify four ER negative-specific breast cancer risk loci. 23535733 2013
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.500 Biomarker disease CTD_human Genome-wide association studies identify four ER negative-specific breast cancer risk loci. 23535733 2013
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.400 Biomarker disease CTD_human HDMX regulates p53 activity and confers chemoresistance to 3-bis(2-chloroethyl)-1-nitrosourea. 20472715 2010
CUI: C0035335
Disease: Retinoblastoma
Retinoblastoma 		0.400 GenomicAlterations disease CGI
CUI: C1261473
Disease: Sarcoma
Sarcoma 		0.380 GenomicAlterations group CGI
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.340 Biomarker group CTD_human Genome-wide association studies identify four ER negative-specific breast cancer risk loci. 23535733 2013
CUI: C0005684
Disease: Malignant neoplasm of urinary bladder
Malignant neoplasm of urinary bladder 		0.330 GenomicAlterations disease CGI
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.320 GenomicAlterations disease CGI
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder 		0.320 GenomicAlterations disease CGI
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.310 Biomarker disease PSYGENET These results suggest that MRP1 polymorphisms may be a predictive marker of citalopram treatment in major depression. 20520284 2010
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.310 Biomarker disease PSYGENET These results suggest that MRP1 polymorphisms may be a predictive marker of citalopram treatment in major depression. 20520284 2010
CUI: C0004681
Disease: Bagassosis
Bagassosis 		0.300 Biomarker disease CTD_human Pathway analysis for a genome-wide association study of pneumoconiosis. 25445010 2015
CUI: C0032273
Disease: Pneumoconiosis
Pneumoconiosis 		0.300 Biomarker disease CTD_human Pathway analysis for a genome-wide association study of pneumoconiosis. 25445010 2015
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human 		0.300 Biomarker disease CTD_human Genome-wide association studies identify four ER negative-specific breast cancer risk loci. 23535733 2013
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human 		0.300 Biomarker disease CTD_human Genome-wide association studies identify four ER negative-specific breast cancer risk loci. 23535733 2013
CUI: C0334588
Disease: Giant Cell Glioblastoma
Giant Cell Glioblastoma 		0.300 Biomarker disease CTD_human HDMX regulates p53 activity and confers chemoresistance to 3-bis(2-chloroethyl)-1-nitrosourea. 20472715 2010
CUI: C0154017
Disease: Benign neoplasm of bladder
Benign neoplasm of bladder 		0.300 GenomicAlterations disease CGI
CUI: C0154091
Disease: Carcinoma in situ of bladder
Carcinoma in situ of bladder 		0.300 GenomicAlterations disease CGI
CUI: C0496930
Disease: Neoplasm of uncertain or unknown behavior of bladder
Neoplasm of uncertain or unknown behavior of bladder 		0.300 GenomicAlterations disease CGI