MMP9, matrix metallopeptidase 9, 4318

N. diseases: 1337; N. variants: 31
Disease: tumor vasculature ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1658953
Disease: tumor vasculature
tumor vasculature 		0.030 Biomarker phenotype BEFREE Our findings revealed that fibroblasts enhance breast carcinoma growth by promoting the tumor vasculature via the MMP9-dependent mechanism. 28423685 2017
CUI: C1658953
Disease: tumor vasculature
tumor vasculature 		0.030 AlteredExpression phenotype BEFREE These data suggest that Ad-uPAR-MMP-9 shows its antitumor activity against both established and early phases of lung cancer metastases by causing the destruction of the tumor vasculature. 16170032 2005
CUI: C1658953
Disease: tumor vasculature
tumor vasculature 		0.030 Biomarker phenotype BEFREE Using a series of bone marrow transplantation experiments in MMP-9(+/+) and MMP-9(-/-) mice xenotransplanted with human neuroblastoma tumors, we show that bone marrow-derived MMP-9 is critical for the recruitment of leukocytes from bone marrow into the tumor stroma and for the integration of bone marrow-derived endothelial cells into the tumor vasculature. 15833851 2005