MMP9, matrix metallopeptidase 9, 4318

N. diseases: 1337; N. variants: 31
Disease: Aortic Stiffness ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3178782
Disease: Aortic Stiffness
Aortic Stiffness 		0.030 AlteredExpression phenotype BEFREE In conclusion, metabolic syndrome causes tPVAT dysfunction through an interplay between TNFα and NOX2 that leads to tPVAT-mediated aortic stiffness by activation of aortic reactive oxygen species and increased MMP9 activity. 29349831 2018
CUI: C3178782
Disease: Aortic Stiffness
Aortic Stiffness 		0.030 GeneticVariation phenotype BEFREE In conclusion, MMP-9 but not MMP-3 polymorphism exerts a modulating influence on aortic stiffness and aortic root dilation in patients after TOF repair. 20541269 2011
CUI: C3178782
Disease: Aortic Stiffness
Aortic Stiffness 		0.030 GeneticVariation phenotype BEFREE This is the first study to show the effect of MMP-9 polymorphism on BP and aortic stiffness in a hypertensive population. 17581602 2007