MIR342, microRNA 342, 442909

N. diseases: 111; N. variants: 0
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.320 AlteredExpression group BEFREE We demonstrated the clinical relevance of the miRNAs and identified miR-342-5p and miR-744* as significantly down-regulated in HER2-positive breast tumors as compared to HER2-negative tumors from two cohorts of breast cancer patients (101 and 1302 cases). miR-342-5p specifically inhibited HER2-positive cell growth, as it had no effect on the growth of HER2-negative control cells in vitro. 24148764 2014
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.320 AlteredExpression group BEFREE Expression of miR-342 was also reduced in a panel of tamoxifen refractory human breast tumors, underscoring the potential clinical importance of miR-342 downregulation. 21172025 2010
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.320 Biomarker group CTD_human Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. 20099276 2010