NPPC, natriuretic peptide C, 4880

N. diseases: 106; N. variants: 2
Disease: Anovulation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003128
Disease: Anovulation
Anovulation 		0.020 AlteredExpression phenotype BEFREE Dehydroepiandrosterone (DHEA) treatment caused anovulation, high levels of androgen and estrogen receptors (AR and ER) in the ovary, high expression of CNP and natriuretic peptide receptor 2 (NPR2) in granulosa cells (GC), and an increase in testosterone and estradiol (E<sub>2</sub>) levels in sera. 29739821 2018
CUI: C0003128
Disease: Anovulation
Anovulation 		0.020 AlteredExpression phenotype BEFREE High level of C-type natriuretic peptide induced by hyperandrogen-mediated anovulation in polycystic ovary syndrome mice. 29535265 2018