PGR, progesterone receptor, 5241

N. diseases: 51; N. variants: 3
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014175
Disease: Endometriosis
Endometriosis 		0.600 Biomarker disease CTD_human Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis. 21232532 2011
CUI: C0014175
Disease: Endometriosis
Endometriosis 		0.600 Biomarker disease CTD_human Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis. 20864642 2011
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.400 Biomarker disease CTD_human Altered expression of genes involved in progesterone biosynthesis, metabolism and action in endometrial cancer. 23200943 2013
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.400 Biomarker disease CTD_human Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization. 21501481 2011
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.400 Biomarker disease CTD_human Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization. 21501481 2011
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker group CTD_human Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization. 21501481 2011
CUI: C0025286
Disease: Meningioma
Meningioma 		0.400 Biomarker disease CTD_human Regression of multiple intracranial meningiomas after cessation of long-term progesterone agonist therapy. 19731987 2010
CUI: C0025286
Disease: Meningioma
Meningioma 		0.400 Biomarker disease CTD_human In the clinical samples of meningioma, the levels of cathepsins B and L, stefin B, and cystatin C were highest in the tumors of higher histological grades, whereas stefin A and progesterone receptor were the only markers that were significantly increased and decreased, respectively, in WHO Grade III lesions. 19747051 2010
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.400 Biomarker disease CTD_human Expression of ER, progesterone receptor, and HER2 proteins and the Ki67 index appear to distinguish luminal A from luminal B breast cancer subtypes. 19436038 2009
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.400 Biomarker disease CTD_human Expression of ER, progesterone receptor, and HER2 proteins and the Ki67 index appear to distinguish luminal A from luminal B breast cancer subtypes. 19436038 2009
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker group CTD_human Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. 19436038 2009
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.400 Biomarker group CTD_human Distinct DNA methylation profiles in malignant mesothelioma, lung adenocarcinoma, and non-tumor lung. 15639718 2005
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.400 Biomarker group CTD_human Quantitative real-time polymerase chain reaction demonstrated that ER alpha, ER beta and PR were statistically elevated by 3-, 4- and 8-fold in carcinomas compared with normal mammary glands. 15637090 2005
CUI: C0025286
Disease: Meningioma
Meningioma 		0.400 Biomarker disease CTD_human Sphenoid wing meningioma progression after placement of a subcutaneous progesterone agonist contraceptive implant. 8008172 1994
CUI: C1849699
Disease: Progesterone Resistance
Progesterone Resistance 		0.400 Biomarker disease CTD_human
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms 		0.390 Biomarker group CTD_human Altered expression of genes involved in progesterone biosynthesis, metabolism and action in endometrial cancer. 23200943 2013
CUI: C0269102
Disease: Endometrioma
Endometrioma 		0.320 Biomarker disease CTD_human Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis. 21232532 2011
CUI: C0269102
Disease: Endometrioma
Endometrioma 		0.320 Biomarker disease CTD_human Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis. 20864642 2011
CUI: C0281784
Disease: Benign Meningioma
Benign Meningioma 		0.310 Biomarker disease CTD_human Regression of multiple intracranial meningiomas after cessation of long-term progesterone agonist therapy. 19731987 2010
CUI: C0281784
Disease: Benign Meningioma
Benign Meningioma 		0.310 Biomarker disease CTD_human Toward understanding recurrent meningioma: the potential role of lysosomal cysteine proteases and their inhibitors. 19747051 2010
CUI: C0347515
Disease: Spinal Meningioma
Spinal Meningioma 		0.310 Biomarker disease CTD_human Toward understanding recurrent meningioma: the potential role of lysosomal cysteine proteases and their inhibitors. 19747051 2010
CUI: C0347515
Disease: Spinal Meningioma
Spinal Meningioma 		0.310 Biomarker disease CTD_human Regression of multiple intracranial meningiomas after cessation of long-term progesterone agonist therapy. 19731987 2010
CUI: C1384406
Disease: Secretory meningioma
Secretory meningioma 		0.310 Biomarker disease CTD_human Regression of multiple intracranial meningiomas after cessation of long-term progesterone agonist therapy. 19731987 2010
CUI: C1384406
Disease: Secretory meningioma
Secretory meningioma 		0.310 Biomarker disease CTD_human Toward understanding recurrent meningioma: the potential role of lysosomal cysteine proteases and their inhibitors. 19747051 2010
CUI: C1565951
Disease: Sphenoid Wing Meningioma
Sphenoid Wing Meningioma 		0.310 Biomarker disease CTD_human Regression of multiple intracranial meningiomas after cessation of long-term progesterone agonist therapy. 19731987 2010