|
Hypertensive disease
|
0.400 |
Therapeutic
|
group |
CTD_human |
Acute glucocorticoid (corticosterone) hypertension in the rate is significantly attenuated by neomycin administration (Honour 1981), as is ACTH-induced hypertension is the same species (Honour & Kent 1981) presumably by altering gut bacterial steroid metabolism.
|
6097376 |
1985 |
|
Hypertensive disease
|
0.400 |
Therapeutic
|
group |
CTD_human |
Potentiation of ACTH hypertension in man with salt loading.
|
2992854 |
1985 |
|
Hypertensive disease
|
0.400 |
Therapeutic
|
group |
CTD_human |
Role of the sympathetic nervous system in the onset of hypertension in the rat: the effect of 6-OH-dopamine.
|
1649024 |
1991 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
These findings expand on the clinical spectrum of phenotypes associated with KCNJ5 mutations and implicate these mutations in the pathogenesis of hypertension associated with increased aldosterone response to ACTH stimulation.
|
27293068 |
2016 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
CTD_human |
This result indicates that the cardiac glycoside binding site of the alpha1 isoform can also mediate ACTH-induced hypertension.
|
16243970 |
2005 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
BEFREE |
PNAH was associated with cushingoid features, virilization and hypertension with a lack of cortisol suppression on high DST, undetectable plasma ACTH and absent cortisol and ACTH responses to CRH.
|
15521956 |
2004 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
BEFREE |
The correlation between excretion of aldosterone and cortisol metabolites and suggests that, in TT subjects, ACTH exerts an important common regulatory influence on adrenal corticosteroid production in subjects with hypertension.
|
17651452 |
2007 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
CTD_human |
Effects of bromocriptine on blood pressure and plasma beta-endorphin in spontaneously hypertensive rats.
|
6274577 |
1981 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
BEFREE |
Hypertension occurred in 34/77 children (44%) during treatment with ACTH and 4/11 children (36%) during treatment with prednisolone.
|
31769329 |
2020 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
CTD_human |
Vasodilator prostanoids and ACTH-dependent hypertension.
|
6135010 |
1983 |
|
Hypertensive disease
|
0.400 |
Therapeutic
|
group |
CTD_human |
Adrenocorticotrophic hormone-induced hypertension in the rat: effects of the endothelin antagonist bosentan.
|
10474778 |
1999 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Hypertension and severe hypokalaemia associated with ectopic ACTH production.
|
30115708 |
2018 |
|
Hypertensive disease
|
0.400 |
Therapeutic
|
group |
CTD_human |
The anti-oxidant Tempol reverses and partially prevents adrenocorticotrophic hormone-induced hypertension in the rat.
|
12872045 |
2003 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
CTD_human |
Thus, NAC partially prevented but did not reverse ACTH-induced hypertension.
|
16546835 |
2006 |
|
Hypertensive disease
|
0.400 |
Therapeutic
|
group |
CTD_human |
ACTH hypertension in the rat: role of sodium chloride.
|
1321011 |
1992 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
BEFREE |
Therefore, the present study provides important information for understanding the mechanism of ACTH-induced hypertension.
|
11082157 |
2000 |
|
Hypertensive disease
|
0.400 |
Therapeutic
|
group |
CTD_human |
L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat.
|
11193135 |
2000 |
|
Hypertensive disease
|
0.400 |
Therapeutic
|
group |
CTD_human |
Lipopolysaccharide reverses adrenocorticotrophic hormone-induced hypertension in the rat.
|
12887135 |
2003 |
|
Hypertensive disease
|
0.400 |
Therapeutic
|
group |
CTD_human |
These studies suggest that a steroid other than aldosterone, 18-OH-DOC, or DOC may be the cause of the ACTH-induced hypertension in this patient.
|
187612 |
1976 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
CTD_human |
Exaggerated natriuresis in ACTH hypertension in sheep.
|
216942 |
1978 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
CTD_human |
Influence of somatostatin analogue (SMS 201-995, octreotide) on blood pressure in adrenocorticotrophin (ACTH) treated rats: role of hyperinsulinaemia in ACTH hypertension.
|
8261660 |
1993 |
|
Hypertensive disease
|
0.400 |
Therapeutic
|
group |
CTD_human |
Dexamethasone-responsive hypertension in young women with suppressed renin and aldosterone.
|
76749 |
1978 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
CTD_human |
Effect of sodium depletion on pressor responsiveness in ACTH-induced hypertension in man.
|
2822310 |
1987 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
CTD_human |
Potentiation of ACTH hypertension in man with salt loading.
|
2992854 |
1985 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
CTD_human |
Children who develop hypertension during ACTH therapy should be considered at risk for hypertrophic cardiomyopathy and should undergo routine echocardiographic evaluation.
|
2821097 |
1987 |