MAPK3, mitogen-activated protein kinase 3, 5595

N. diseases: 647; N. variants: 7
Disease: Cerebral Infarction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.060 AlteredExpression disease BEFREE The mRNA expressions of ERK1 and ERK2 in neural stem cells increased in a time-dependent manner after cerebral infarction in rats. 31298390 2019
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.060 Biomarker disease BEFREE S1P<sub>2</sub> contributes to microglial activation and M1 polarization following cerebral ischemia through ERK1/2 and JNK. 31431671 2019
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.060 Biomarker disease BEFREE Clonidine preconditioning improved cerebral ischemia-induced learning and memory deficits in rats via ERK1/2-CREB/ NF-κB-NR2B pathway. 29074416 2018
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.060 AlteredExpression disease BEFREE Neuroprotective effects of Tongxinluo on focal cerebral ischemia and reperfusion injury in rats associated with the activation of the MEK1/2/ERK1/2/p90RSK signaling pathway. 29425910 2018
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.060 Biomarker disease BEFREE Icariin and mesenchymal stem cells synergistically promote angiogenesis and neurogenesis after cerebral ischemia via PI3K and ERK1/2 pathways. 30245466 2018
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.060 AlteredExpression disease BEFREE Irisin reduces ischemia-induced neuronal injury via activation of the Akt and ERK1/2 signaling pathways and contributes to the neuroprotective effect of physical exercise against cerebral ischemia, suggesting that irisin may be a factor linking metabolism and cardio-cerebrovascular diseases. 28183451 2017