MAPK3, mitogen-activated protein kinase 3, 5595

N. diseases: 647; N. variants: 7
Disease: Cholesteatoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008373
Disease: Cholesteatoma
Cholesteatoma 		0.020 AlteredExpression disease BEFREE We demonstrated increased levels of involucrin and increased levels of the activated forms of p38 and ERK1/2 in cholesteatoma epithelium when compared with control samples. 16639284 2006
CUI: C0008373
Disease: Cholesteatoma
Cholesteatoma 		0.020 AlteredExpression disease LHGDN A total of 18 cholesteatoma samples and 18 paired control retro-auricular skin samples were immunohistochemically stained for p53, p21, phosphorylated ERK1/2 (pERK1/2) and total ERK1/2. 15880942 2005
CUI: C0008373
Disease: Cholesteatoma
Cholesteatoma 		0.020 Biomarker disease BEFREE We designed the present study to investigate whether the RAS/RAF/ERK1/2 MAPK signalling pathway is involved in p53-dependent and p21-mediated cell cycle arrest in human cholesteatoma. 15880942 2005