Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.400 Biomarker disease CTD_human Hepatocellular carcinoma-associated protein markers investigated by MALDI-TOF MS. 21472284 2012
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.400 Therapeutic group CTD_human Reduced 293T cell susceptibility to acrolein due to aldose reductase-like-1 protein expression. 17329238 2007
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.400 Therapeutic group CTD_human Reduced 293T cell susceptibility to acrolein due to aldose reductase-like-1 protein expression. 17329238 2007
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 Biomarker disease CTD_human To evaluate its potential as a target for cancer intervention, in the current study we knocked down AKR1B10 expression in HCT-8 cells derived from a colorectal carcinoma, using chemically synthesized small interfering RNA (siRNA). 17597105 2007
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.330 Biomarker disease CTD_human To date, there have been no reports on the expression of AKR1B1 in endometrial cancer, while AKR1B10 has only been studied at the cellular level. 23146748 2013
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.310 Biomarker group CTD_human Aldo-keto reductase family 1 B10 gene silencing results in growth inhibition of colorectal cancer cells: Implication for cancer intervention. 17597105 2007
CUI: C0086692
Disease: Benign Neoplasm
Benign Neoplasm 		0.310 Therapeutic group CTD_human Reduced 293T cell susceptibility to acrolein due to aldose reductase-like-1 protein expression. 17329238 2007
CUI: C0011616
Disease: Contact Dermatitis
Contact Dermatitis 		0.300 Biomarker disease CTD_human Genes specifically modulated in sensitized skins allow the detection of sensitizers in a reconstructed human skin model. Development of the SENS-IS assay. 25724174 2015
CUI: C0027626
Disease: Neoplasm Invasiveness
Neoplasm Invasiveness 		0.300 Biomarker phenotype CTD_human Acquisition of doxorubicin resistance facilitates migrating and invasive potentials of gastric cancer MKN45 cells through up-regulating aldo-keto reductase 1B10. 25686905 2015
CUI: C0162351
Disease: Contact hypersensitivity
Contact hypersensitivity 		0.300 Biomarker phenotype CTD_human Genes specifically modulated in sensitized skins allow the detection of sensitizers in a reconstructed human skin model. Development of the SENS-IS assay. 25724174 2015
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms 		0.300 Biomarker group CTD_human Decreased levels of AKR1B1 and AKR1B10 in cancerous endometrium compared to adjacent non-cancerous tissue. 23146748 2013
CUI: C0025202
Disease: melanoma
melanoma 		0.300 Biomarker disease CTD_human Exome sequencing identifies GRIN2A as frequently mutated in melanoma. 21499247 2011