Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
miR-410-3p acts as an oncogene or a tumor suppressor in some malignancies.
|
30242542 |
2019 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Therefore, miR-410-3p may serve as a novel tumor suppressor gene in RMS, and could possess diagnostic and therapeutic potentials for the treatment of RMS.
|
31289572 |
2019 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
miR-410-3p acts as an oncomiR in gonadotroph and corticotroph adenoma cells, while as a tumor suppressor miR in somatotroph adenoma cells.
|
31165412 |
2019 |
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
RT-PCR validation demonstrated three downregulated miRNAs in F-CAFs compared with NFs (miR-145-3p, miR-299-3p, and miR-505-3p), two in F-CAFs compared with In-CAFs (miR-410-3p and miR-485-5p), but no differentially expressed miRNAs between In-CAFs and NFs.
|
30369556 |
2018 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
MiR-410 Acts as a Tumor Suppressor in Estrogen Receptor-Positive Breast Cancer Cells by Directly Targeting ERLIN2 via the ERS Pathway.
|
30016800 |
2018 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Low miR-410-3p expression correlated with gemcitabine resistance in HPCx tumors and PDAC cells as well as poor prognosis in PDAC patients.
|
29296182 |
2017 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
miR-410-3p acts as an oncogene or tumor-suppressor gene in various types of cancer.
|
27221455 |
2016 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
MicroRNA-410 functions as a tumor suppressor by targeting angiotensin II type 1 receptor in pancreatic cancer.
|
25646808 |
2015 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
miR-410 acts as an oncogene or tumor suppressor gene in some malignancies.
|
26149213 |
2015 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Downregulation of miR-410 targeting the cyclin B1 gene plays a role in pituitary gonadotroph tumors.
|
26125663 |
2015 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Finally, overexpression of miR-410 also showed a negative effect on tumor growth in vivo.
|
25385479 |
2015 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Tangeretin triggered the upregulation of miR-410, a tumor-suppressive microRNA.
|
25998143 |
2015 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Thus, our findings suggested that miR-410 acted as a new tumor suppressor by targeting the MDM2 gene and inhibiting gastric cancer cells proliferation, migration and invasion.
|
25136862 |
2014 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Two miRNA signatures: miR-92a/miR-410 and miR-92a/miR-205/miR-410 classified tumor tissues with higher accuracy in comparison to single miRNAs (AUC: 0.977, 95% CI: 0.927-0.996 and 0.984, 95% CI: 0.938-0.999, respectively). miRNA signature composed of miR-205 and miR-200a predicted relapse with AUC of 0.854 (95% CI: 0.691-0.951).
|
22987275 |
2013 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Our findings suggest that miR-410, a direct regulator of MET, may function as a tumor suppressor in human gliomas.
|
22750473 |
2012 |