BDNF, brain derived neurotrophic factor, 627

N. diseases: 992; N. variants: 56
Disease: Hyperplasia of pancreatic islet beta cell ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0271706
Disease: Hyperplasia of pancreatic islet beta cell
Hyperplasia of pancreatic islet beta cell 		0.010 AlteredExpression disease BEFREE Chronic GLP-1 (7-36) administration to HFD-induced obese rats elevated c-fos expression and BDNF content in the hypothalamus, followed by a reduction in pancreatic β-cell hyperplasia and insulin content, thus resulting in improved glucose tolerance. 28717164 2017