BDNF, brain derived neurotrophic factor, 627

N. diseases: 992; N. variants: 56
Disease: Distended bowel ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2747824
Disease: Distended bowel
Distended bowel 		0.010 AlteredExpression disease BEFREE We hypothesized that mechanical stress-induced expression of BDNF in smooth muscle cells (SMC) of the distended bowel plays a critical role in visceral hypersensitivity in BO by altering voltage-gated K<sup>+</sup> channel (K<sub>v</sub> ) activity in sensory neurons. 29781158 2018