SKP2, S-phase kinase associated protein 2, 6502

N. diseases: 204; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.070 Biomarker group LHGDN Dissection of the APCCdh1-Skp2 cascade in breast cancer. 18381934 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.070 AlteredExpression group LHGDN The combination of high cyclin E and Skp2 expression in breast cancer is associated with a poor prognosis and the basal phenotype. 18620730 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.070 AlteredExpression group LHGDN FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2. 18008005 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.070 Biomarker group LHGDN Significance of skp2 expression in primary breast cancer. 16489076 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.070 AlteredExpression group LHGDN Prognostic impact of Skp2 and p27 in human breast cancer. 16636894 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.070 AlteredExpression group LHGDN Estrogens down-regulate p27Kip1 in breast cancer cells through Skp2 and through nuclear export mediated by the ERK pathway. 12904306 2003
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.070 Biomarker group LHGDN Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer. 12208864 2002