SLC6A4, solute carrier family 6 member 4, 6532

N. diseases: 75; N. variants: 6
Disease: Unipolar Depression ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.600 Biomarker disease PSYGENET Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET) gene polymorphisms: susceptibility and treatment response of electroconvulsive therapy in treatment resistant depression. 25650523 2015
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.600 Biomarker disease PSYGENET Our study included 2679 participants.Those with both the 5-HTTLPR s allele and the BDNF Met allele showed the highest risk of MD if they had previously experienced emotional (z = 2.08, p = 0.037), sexual (z = 2.19, p = 0.029) or any kind of childhood abuse (z = 2.37, p = 0.018). 25510949 2015
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.600 Biomarker disease PSYGENET Serotonin transporter gene hypomethylation predicts impaired antidepressant treatment response. 24679990 2014
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.600 Biomarker disease PSYGENET Epigenetic and epistatic interactions between serotonin transporter and brain-derived neurotrophic factor genetic polymorphism: insights in depression. 24972302 2014
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.600 Biomarker disease PSYGENET Association between serotonin transporter genotype, brain structure and adolescent-onset major depressive disorder: a longitudinal prospective study. 25226554 2014
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.600 Biomarker disease CTD_human Estradiol and progesterone modify the effects of the serotonin reuptake transporter polymorphism on serotonergic responsivity to citalopram. 21843009 2011
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.600 Biomarker disease CTD_human Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. 18458677 2009
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.600 Biomarker disease CTD_human The association between serotonin transporter gene promoter polymorphism (5-HTTLPR), self-reported symptoms, and dental mercury exposure. 18686203 2008
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.600 Biomarker disease CTD_human Regional serotonin transporter availability and depression are correlated in Wilson's disease. 12898347 2003