TFPI, tissue factor pathway inhibitor, 7035

N. diseases: 230; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042487
Disease: Venous Thrombosis
Venous Thrombosis
0.320 Therapeutic phenotype CTD_human Comparison of anticoagulant effects on vein grafts between human TFPI gene transfection and aspirin oral administration. 18480984 2008
CUI: C0042487
Disease: Venous Thrombosis
Venous Thrombosis
0.320 GeneticVariation phenotype LHGDN Analysis of a T-287C polymorphism in the tissue factor pathway inhibitor gene and identification of a repressor element in the promoter. 17931693 2008
CUI: C0042487
Disease: Venous Thrombosis
Venous Thrombosis
0.320 GeneticVariation phenotype LHGDN These results indicate that the TFPI -33T->C and -399C->T polymorphisms are significantly associated with venous thrombosis in the presence of other risk factors, especially APS, and may be clinically relevant in patients who are prone to hypercoagulability. 17762532 2007