TPH1, tryptophan hydroxylase 1, 7166

N. diseases: 127; N. variants: 11
Disease: Heroin Dependence ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019337
Disease: Heroin Dependence
Heroin Dependence 		0.010 GeneticVariation disease BEFREE At the two locus genotype level in Hispanics, the TPH1 rs1799913 variant was found to significantly interact with the TPH2 rs7963720 variant and heroin addiction (P=0.022), and with the TPH2 rs4290270 variant and heroin addiction (P=0.011). 18181017 2008