Disease: Fetal Growth Retardation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.060 Biomarker phenotype BEFREE These results further highlight a role for placental PHLDA2 in poor perinatal outcomes, specifically FGR associated with RFM. 26944942 2016
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.060 AlteredExpression phenotype BEFREE Placental expression of PHLDA2 in selective intrauterine growth restriction in monozygotic twins. 24703004 2014
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.060 AlteredExpression phenotype BEFREE When compared to age-matched appropriate for gestational age (AGA) infants, expression of PHLDA2 (p = 0.03) IGF2R (p < 0.05) was upregulated in IUGR infants. 22154689 2012
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.060 Biomarker phenotype BEFREE The results suggest that placental PHLDA2 may provide a biomarker for suboptimal skeletal growth in pregnancies uncomplicated by overt fetal growth restriction. 22100507 2012
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.060 AlteredExpression phenotype BEFREE Nine of the 52 (17%) expressed genes were significantly differentially expressed between normal and IUGR placentas; five were upregulated (PHLDA2, ILK2, NNAT, CCDC86, PEG10) and four downregulated (PLAGL1, DHCR24, ZNF331, CDKAL1). 19483473 2009
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.060 AlteredExpression phenotype BEFREE In this series six imprinted genes were differentially expressed by ANOVA with a Benjamini-Hochberg false discovery rate of 0.05, with increased expression of PHLDA2 and decreased expression of MEST, MEG3, GATM, GNAS and PLAGL1 in IUGR placentae. 16125225 2006