TYK2, tyrosine kinase 2, 7297

N. diseases: 172; N. variants: 22
Disease: Malignant Peripheral Nerve Sheath Tumor ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751690
Disease: Malignant Peripheral Nerve Sheath Tumor
Malignant Peripheral Nerve Sheath Tumor 		0.020 AlteredExpression disease BEFREE We have demonstrated that TYK2 was highly expressed in the majority of human MPNSTs examined. 31278855 2019
CUI: C0751690
Disease: Malignant Peripheral Nerve Sheath Tumor
Malignant Peripheral Nerve Sheath Tumor 		0.020 GeneticVariation disease BEFREE Clinical genomic analysis of the current series of NF1-MPNST cases found that TYK2 is a new gene mutated in MPNST. 27875628 2017