MIR770, microRNA 770, 768222

N. diseases: 27; N. variants: 0
Disease: Non-Small Cell Lung Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.020 Biomarker disease BEFREE Moreover, we found that the diagnostic value of serum miR-770 for NSCLC patients from healthy controls resulted in an AUC of 0.835 (95 % CI, 0.751-0.919) with a sensitivity of 68% and a specificity of 89%, based on a cut-off value of 5.723. 29863251 2018
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.020 AlteredExpression disease BEFREE We first showed that miR-770 was downregulated in NSCLC tissues and cell lines, and the low expression of miR-770 was correlated with poor patient survival in NSCLC patients. miR-770 acted on a tumor suppressor by binding to the 3'UTR of JMJD6 and downregulated its expression in NSCLC cells. 28882645 2017