HPP1, hyperpigmentation, progressive, 1, 780897

N. diseases: 35; N. variants: 0
Disease: Hyperplastic Polyp ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0333983
Disease: Hyperplastic Polyp
Hyperplastic Polyp 		0.020 AlteredExpression disease BEFREE Expression of the DNA mismatch repair gene hMLH1 is diminished or absent in some hyperplastic polyps, and it has been suggested that HPP1 inactivation is associated with the progression of microsatellite-unstable colorectal tumors. 12384516 2002
CUI: C0333983
Disease: Hyperplastic Polyp
Hyperplastic Polyp 		0.020 PosttranslationalModification disease BEFREE The HPP1 gene was cloned as a frequently methylated gene in hyperplastic polyps of the colon. 12460892 2002