Disease: Diabetic Retinopathy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy 		0.070 Biomarker disease BEFREE We performed two studies in humans.In study 1, we investigated the effect of GLP-1RA exposure from T2D diagnosis on the severity of DR, as diagnosed with retinal imaging (fundus photography). 31589290 2020
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy 		0.070 Biomarker disease BEFREE New Insights into the Mechanisms of Action of Topical Administration of GLP-1 in an Experimental Model of Diabetic Retinopathy. 30862093 2019
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy 		0.070 Biomarker disease BEFREE Treatment with GLP-1 RAs did not increase incidence of diabetic retinopathy, macular oedema, retinal detachment and retinal haemorrhage, irrespective of comparator. 30058208 2019
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy 		0.070 GeneticVariation disease BEFREE Compared with insulin, GLP-1 RAs were associated with a decreased risk of diabetic retinopathy (HR 0.67, 95% CI 0.51-0.90). 30150234 2018
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy 		0.070 Biomarker disease BEFREE In this review, we discuss the potential protective mechanisms of GLP-1RA for DR beyond the hypoglycemic effects. 28807775 2018
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy 		0.070 Biomarker disease BEFREE Current evidence indicates that the association between DPP-4i, GLP-1RA or SGLT2 inhibitors and risk of DR remains uncertain in patients with T2DM. 29369494 2018
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy 		0.070 AlteredExpression disease BEFREE <b>Results:</b> GLP-1treatment reduced the levels of NOX3 and SOD2 in DR. 29104476 2017