Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia
0.030 AlteredExpression disease BEFREE A tumor suppressor protein, stromal antigen 2 (STAG2), has recurrent mutations or loss of expression in many tumors including in bladder cancer, osteosarcoma (OS), and leukemia. 31157248 2019
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia
0.030 Biomarker disease BEFREE The tumor suppressor protein p53 is inactive in a large number of cancers, including some forms of sarcoma, breast cancer, and leukemia, due to overexpression of its intrinsic inhibitors MDM2 and MDMX. 31390185 2019
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia
0.030 PosttranslationalModification disease BEFREE We will review, in depth, the role of CK2 in leukemia and its mechanisms of tumorigenesis via phosphorylation of the tumor suppressor protein Ikaros. 27719640 2017