ADO, 2-aminoethanethiol dioxygenase, 84890

N. diseases: 41; N. variants: 3
Disease: Immunosuppression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.020 Biomarker disease BEFREE Moreover, the expression of the enzyme responsible for the degradation of ADO, adenosine deaminase, was higher in tolerant patients with respect to the nontolerant group along the immunosuppression withdrawal. 30019408 2019
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.020 GeneticVariation disease BEFREE However, the basis for immunosuppression by Ado has not been well defined, and effects of 2'-deoxyadenosine (dAdo), which does not activate Ado receptors, have also been implicated in causing SCID. 15580654 2005