HDAC3, histone deacetylase 3, 8841

N. diseases: 179; N. variants: 5
Disease: Malignant neoplasm of pancreas ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.030 Biomarker disease BEFREE More importantly, these data suggest that the HDAC3 inhibitors might be used to improve immunotherapy in pancreatic cancer. 30670333 2019
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.030 Biomarker disease BEFREE HDAC3 mediates smoking-induced pancreatic cancer. 26745602 2016
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.030 Biomarker disease BEFREE Taken together, our data suggest that HDAC3 participates in the pathogenesis and progression of pancreatic cancer through histone modification, which might be a pivotal epigenetic target against this devastating disease. 25070540 2014