ISX, intestine specific homeobox, 91464

N. diseases: 16; N. variants: 1
Disease: IMMUNE SUPPRESSION ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1840264
Disease: IMMUNE SUPPRESSION
IMMUNE SUPPRESSION 		0.010 Biomarker phenotype BEFREE Overall, our results identified a feed-forward mechanism of immune suppression in hepatocellular carcinoma organized by ISX, which involves kynurenine-AHR signaling and PD-L1, offering insights into immune escape by hepatocellular carcinoma, which may improve its therapeutic management.<i></i>. 28625979 2017