|
Kidney Failure, Chronic
|
0.600 |
Biomarker
|
disease |
CTD_human |
Increased production of proinflammatory cytokines in adipose tissue of patients with end-stage renal disease.
|
19539174 |
2009 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
Biomarker
|
disease |
CTD_human |
We investigated the single nucleotide polymorphisms (SNPs) +45T/G and +276G/T of the adiponectin gene as predictors for the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial, which aimed to investigate the effect of acarbose compared with placebo on the prevention of type 2 diabetes.
|
15734870 |
2005 |
|
Gestational Diabetes
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Adiponectin concentrations were statistically significantly lower in women with GDM than controls (4.4 vs. 8.1 micro g/ml, P < 0.001).
|
15126557 |
2004 |
|
Obesity
|
0.600 |
Therapeutic
|
disease |
CTD_human |
Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats.
|
14617771 |
2003 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
CTD_human |
Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats.
|
14617771 |
2003 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
Biomarker
|
disease |
CTD_human |
Adiponectin and development of type 2 diabetes in the Pima Indian population.
|
12114044 |
2002 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
Biomarker
|
disease |
CTD_human |
Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians.
|
12354786 |
2002 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
CTD_human |
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity.
|
10092513 |
1999 |
|
Obesity
|
0.600 |
Therapeutic
|
disease |
CTD_human |
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity.
|
10092513 |
1999 |
|
Insulin Resistance
|
0.500 |
Therapeutic
|
phenotype |
CTD_human |
Dual acting and pan-PPAR activators as potential anti-diabetic therapies.
|
21484566 |
2011 |
|
Insulin Resistance
|
0.500 |
Therapeutic
|
phenotype |
CTD_human |
Adiponectin is an adipocyte-derived protein that acts to reduce insulin resistance in the liver and muscle and also inhibits atherosclerosis.
|
18931039 |
2009 |
|
Hypoadiponectinemia
|
0.500 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
Renal Cell Carcinoma
|
0.400 |
Biomarker
|
disease |
CTD_human |
The aim of the present study was to explore the relationship between adiponectin gene (ADIPOQ) polymorphisms and RCC and investigate whether individuals with an ADIPOQ risk genotype, obesity, and high urinary total arsenic levels have a modified odds ratio (OR) of RCC.
|
29723618 |
2018 |
|
Hyperglycemia
|
0.400 |
Therapeutic
|
disease |
CTD_human |
A collagen domain-derived short adiponectin peptide activates APPL1 and AMPK signaling pathways and improves glucose and fatty acid metabolisms.
|
29991592 |
2018 |
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
0.400 |
Biomarker
|
disease |
CTD_human |
The aim of the present study was to explore the relationship between adiponectin gene (ADIPOQ) polymorphisms and RCC and investigate whether individuals with an ADIPOQ risk genotype, obesity, and high urinary total arsenic levels have a modified odds ratio (OR) of RCC.
|
29723618 |
2018 |
|
Heart failure
|
0.400 |
Biomarker
|
disease |
CTD_human |
Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice.
|
26670611 |
2016 |
|
Heart failure
|
0.400 |
Therapeutic
|
disease |
CTD_human |
Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice.
|
26670611 |
2016 |
|
Congestive heart failure
|
0.400 |
Therapeutic
|
disease |
CTD_human |
Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice.
|
26670611 |
2016 |
|
Congestive heart failure
|
0.400 |
Biomarker
|
disease |
CTD_human |
Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice.
|
26670611 |
2016 |
|
Non-alcoholic Fatty Liver Disease
|
0.400 |
Biomarker
|
disease |
CTD_human |
Adiponectin generally predicts steatosis grade and severity of NAFLD, but it remains to be addressed to what extent this is a direct effect or related to the presence of more severe IR.
|
20415685 |
2010 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
CTD_human |
Hypoadiponectinemia is strongly associated with metabolic syndrome in Korean type 2 diabetes patients.
|
20833989 |
2010 |
|
Atherosclerosis
|
0.400 |
Therapeutic
|
disease |
CTD_human |
Adiponectin is an adipocyte-derived protein that acts to reduce insulin resistance in the liver and muscle and also inhibits atherosclerosis.
|
18931039 |
2009 |
|
Heart failure
|
0.400 |
Biomarker
|
disease |
CTD_human |
Effect of carvedilol on plasma adiponectin concentration in patients with chronic heart failure.
|
19367012 |
2009 |
|
Heart failure
|
0.400 |
Therapeutic
|
disease |
CTD_human |
Effect of carvedilol on plasma adiponectin concentration in patients with chronic heart failure.
|
19367012 |
2009 |
|
Congestive heart failure
|
0.400 |
Therapeutic
|
disease |
CTD_human |
Effect of carvedilol on plasma adiponectin concentration in patients with chronic heart failure.
|
19367012 |
2009 |