CD40LG, CD40 ligand, 959

N. diseases: 453; N. variants: 25
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis
0.220 Biomarker disease BEFREE Activation of platelets promotes secretion of CD40L that induces sepsis and multiple organ dysfunction syndrome (MODS). 29956071 2018
CUI: C0243026
Disease: Sepsis
Sepsis
0.220 AlteredExpression disease BEFREE We hypothesized that matrix metalloproteinase (MMP)-9 might cleave surface-expressed CD40L and regulate pulmonary accumulation of neutrophils in sepsis. 23617547 2013
CUI: C0243026
Disease: Sepsis
Sepsis
0.220 Biomarker disease RGD Norepinephrine induces systolic failure and inhibits antiapoptotic genes in a polymicrobial septic rat model. 20933523 2010