CD40LG, CD40 ligand, 959

N. diseases: 453; N. variants: 25
Disease: Central visual impairment ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3810365
Disease: Central visual impairment
Central visual impairment 		0.010 AlteredExpression disease BEFREE The observation that both gene and surface expression of gp39 by activated T cells is depressed in a subgroup of CVI patients suggests that inefficient signaling via CD40 may be responsible, in part, for failure of B-cell differentiation in these patients. 7508119 1994