CDC6, cell division cycle 6, 990

N. diseases: 130; N. variants: 3
Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.330 Biomarker disease BEFREE Cell division cycle 6 (CDC6), minichromosome maintenance complex component 4 (MCM4) and MCM8, which serve pivotal functions in the occurrence and development of HCC, were the most significant hub genes. 30546424 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.330 Biomarker disease CTD_human Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling. 28284560 2017
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.330 GeneticVariation disease BEFREE Here we examined the influence of this polymorphism on the function of Cdc6 and the individual's susceptibility to non-Hodgkin lymphoma (NHL) and hepatocellular carcinoma (HCC). 19101572 2009
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.330 AlteredExpression disease BEFREE These results indicate that the individuals with G allele may have reduced Cdc6 expression and are therefore in reduced risk for HCC. 18640135 2008
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.330 GeneticVariation disease LHGDN These results indicate that the individuals with G allele may have reduced Cdc6 expression and are therefore in reduced risk for HCC. 18640135 2008