CFHR4, complement factor H related 4, 10877

N. diseases: 11; N. variants: 15
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6685931
rs6685931
Entrez Id: 10877
Gene Symbol: CFHR4
CFHR4
CUI: C0242383
Disease:
Age related macular degeneration 		0.710 GeneticVariation BEFREE The SNP rs6685931 in CFHR4 and its linked haplotype H1-2 also conferred a risk for AMD development, and therefore could be used to identify AMD patients who would benefit most from complement-inhibiting therapies. 29398083 2018
dbSNP: rs1853883
rs1853883
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C0242383
Disease:
Age related macular degeneration 		0.710 GeneticVariation GWASDB Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 23326517 2013
dbSNP: rs1853883
rs1853883
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C0242383
Disease:
Age related macular degeneration 		0.710 GeneticVariation BEFREE Seventeen single nucleotide polymorphisms (SNPs) in known AMD risk-associated genes including CFH (rs800292, rs3766404, rs1061170, rs2274700 and rs393955), HTRA1 (rs11200638), CFHR1-5 (rs10922153, rs16840639, rs6667243, and rs1853883), LOC387715/ARMS2 (rs3793917 and rs10490924), C3 (rs2230199 and rs1047286), C2 (rs547154), CFB (rs641153) and F13B (rs6003) were examined. 23582991 2013
dbSNP: rs1853883
rs1853883
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C0242383
Disease:
Age related macular degeneration 		0.710 GeneticVariation GWASDB Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis. 23577725 2013
dbSNP: rs6685931
rs6685931
Entrez Id: 10877
Gene Symbol: CFHR4
CFHR4
CUI: C0242383
Disease:
Age related macular degeneration 		0.710 GeneticVariation GWASDB Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 23326517 2013
dbSNP: rs6685931
rs6685931
Entrez Id: 10877
Gene Symbol: CFHR4
CFHR4
CUI: C0242383
Disease:
Age related macular degeneration 		0.710 GeneticVariation GWASDB Sifting the wheat from the chaff: prioritizing GWAS results by identifying consistency across analytical methods. 22125219 2011
dbSNP: rs1853883
rs1853883
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C0242383
Disease:
Age related macular degeneration 		0.710 GeneticVariation GWASDB Genome-wide association analyses of genetic, phenotypic, and environmental risks in the age-related eye disease study. 21197116 2010
dbSNP: rs7367184
rs7367184
Entrez Id: 10877
Gene Symbol: CFHR4
CFHR4
CUI: C0013595
Disease:
Eczema 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs4915559
rs4915559
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C2985280
Disease:
Blood Protein Measurement 		T 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs6685931
rs6685931
Entrez Id: 10877
Gene Symbol: CFHR4
CFHR4
CUI: C2985280
Disease:
Blood Protein Measurement 		T 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs78239784
rs78239784
Entrez Id: 10877
Gene Symbol: CFHR4
CFHR4
CUI: C0423791
Disease:
Maculopapular Lesion 		G 0.700 GeneticVariation GWASCAT Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients. 29288229 2018
dbSNP: rs10494745
rs10494745
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C0523688
Disease:
Hemopexin measurement 		A 0.700 GeneticVariation GWASCAT Connecting genetic risk to disease end points through the human blood plasma proteome. 28240269 2017
dbSNP: rs10494745
rs10494745
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C0242383
Disease:
Age related macular degeneration 		0.700 GeneticVariation GWASDB Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 23326517 2013
dbSNP: rs10801580
rs10801580
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C0242383
Disease:
Age related macular degeneration 		0.700 GeneticVariation GWASDB Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis. 23577725 2013
dbSNP: rs10922147
rs10922147
Entrez Id: 10877
Gene Symbol: CFHR4
CFHR4
CUI: C0242383
Disease:
Age related macular degeneration 		0.700 GeneticVariation GWASDB Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 23326517 2013
dbSNP: rs10922147
rs10922147
Entrez Id: 10877
Gene Symbol: CFHR4
CFHR4
CUI: C2239219
Disease:
von Willebrand's factor (lab test) 		0.700 GeneticVariation GWASDB Ischemic stroke is associated with the ABO locus: the EuroCLOT study. 23381943 2013
dbSNP: rs1409153
rs1409153
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C0242383
Disease:
Age related macular degeneration 		0.700 GeneticVariation GWASDB Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 23326517 2013
dbSNP: rs1853882
rs1853882
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C0242383
Disease:
Age related macular degeneration 		0.700 GeneticVariation GWASDB Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 23326517 2013
dbSNP: rs4915559
rs4915559
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C0242383
Disease:
Age related macular degeneration 		0.700 GeneticVariation GWASDB Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 23326517 2013
dbSNP: rs4915559
rs4915559
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C1167912
Disease:
Coagulation factor measurement 		T 0.700 GeneticVariation GWASCAT Ischemic stroke is associated with the ABO locus: the EuroCLOT study. 23381943 2013
dbSNP: rs4915559
rs4915559
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C2239219
Disease:
von Willebrand's factor (lab test) 		T 0.700 GeneticVariation GWASDB Ischemic stroke is associated with the ABO locus: the EuroCLOT study. 23381943 2013
dbSNP: rs7366238
rs7366238
Entrez Id: 10877
Gene Symbol: CFHR4
CFHR4
CUI: C0242383
Disease:
Age related macular degeneration 		0.700 GeneticVariation GWASDB Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 23326517 2013
dbSNP: rs7366238
rs7366238
Entrez Id: 10877
Gene Symbol: CFHR4
CFHR4
CUI: C2239219
Disease:
von Willebrand's factor (lab test) 		0.700 GeneticVariation GWASDB Ischemic stroke is associated with the ABO locus: the EuroCLOT study. 23381943 2013
dbSNP: rs7525447
rs7525447
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C0242383
Disease:
Age related macular degeneration 		0.700 GeneticVariation GWASDB Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 23326517 2013
dbSNP: rs7533270
rs7533270
Entrez Id: 10877;105371675
Gene Symbol: CFHR4;LOC105371675
CFHR4;LOC105371675
CUI: C0242383
Disease:
Age related macular degeneration 		0.700 GeneticVariation GWASDB Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 23326517 2013