DisGeNET - a database of gene-disease associations

SPRED2, sprouty related EVH1 domain containing 2, 200734

N. diseases: 38; N. variants: 20

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1858037

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.800

GeneticVariation

GWASCAT

Genetic influences on susceptibility to rheumatoid arthritis in African-Americans.

30423114

2019

dbSNP:

rs1858037

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.800

GeneticVariation

GWASDB

Genetics of rheumatoid arthritis contributes to biology and drug discovery.

24390342

2014

dbSNP:

rs1858037

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.800

GeneticVariation

GWASCAT

Genetics of rheumatoid arthritis contributes to biology and drug discovery.

24390342

2014

dbSNP:

rs934734

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.800

GeneticVariation

GWASCAT

Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans.

24782177

2014

dbSNP:

rs934734

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.800

GeneticVariation

GWASDB

Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans.

24782177

2014

dbSNP:

rs11673987

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.800

GeneticVariation

GWASDB

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.

23143596

2012

dbSNP:

rs11673987

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.800

GeneticVariation

GWASCAT

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.

23143596

2012

dbSNP:

rs6546146

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.800

GeneticVariation

GWASCAT

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.

23143596

2012

dbSNP:

rs6546146

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.800

GeneticVariation

GWASDB

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.

23143596

2012

dbSNP:

rs934734

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.800

GeneticVariation

GWASDB

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.

23143596

2012

dbSNP:

rs934734

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.800

GeneticVariation

GWASDB

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.

22446963

2012

dbSNP:

rs1876518

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0021053
Disease:

Immune System Diseases

0.800

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

21383967

2011

dbSNP:

rs1876518

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0004364
Disease:

Autoimmune Diseases

0.800

GeneticVariation

GWASDB

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

21383967

2011

dbSNP:

rs1876518

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0004364
Disease:

Autoimmune Diseases

0.800

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

21383967

2011

dbSNP:

rs1876518

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0021053
Disease:

Immune System Diseases

0.800

GeneticVariation

GWASDB

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

21383967

2011

dbSNP:

rs934734

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.800

GeneticVariation

GWASDB

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.

20453842

2010

dbSNP:

rs934734

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0003873
Disease:

Rheumatoid Arthritis

0.800

GeneticVariation

GWASCAT

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.

20453842

2010

dbSNP:

rs2661794

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0014772
Disease:

Red Blood Cell Count measurement

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs2661794

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C1261502
Disease:

Finding of Mean Corpuscular Hemoglobin

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs268134

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0021704
Disease:

Intelligence

0.700

GeneticVariation

GWASCAT

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.

31374203

2019

dbSNP:

rs268134

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0036341
Disease:

Schizophrenia

0.700

GeneticVariation

GWASCAT

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.

31374203

2019

dbSNP:

rs61748094

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0042834
Disease:

Vital capacity

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs62139120

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0005890
Disease:

Body Height

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs6731993

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0023508
Disease:

White Blood Cell Count procedure

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs7569084

Entrez Id:	200734
Gene Symbol:	SPRED2

SPRED2

CUI:	C0200638
Disease:

Eosinophil count procedure

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019