GSK3B, glycogen synthase kinase 3 beta, 2932

N. diseases: 393; N. variants: 25
Disease: Unipolar Depression ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs334558
rs334558
Entrez Id: 2932;107986119
Gene Symbol: GSK3B;LOC107986119
GSK3B;LOC107986119
CUI: C0041696
Disease:
Unipolar Depression 		0.020 GeneticVariation BEFREE Notably, another promotor SNP (rs334558) of the GSK-3β gene is reportedly associated with unipolar depression, bipolar disorders, and dementia. 31742842 2019
dbSNP: rs334558
rs334558
Entrez Id: 2932;107986119
Gene Symbol: GSK3B;LOC107986119
GSK3B;LOC107986119
CUI: C0041696
Disease:
Unipolar Depression 		0.020 GeneticVariation BEFREE The gender-specific association of rs334558 in GSK3β with major depressive disorder. 28099358 2017
dbSNP: rs2199503
rs2199503
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
CUI: C0041696
Disease:
Unipolar Depression 		0.010 GeneticVariation BEFREE We found rs334535 (Pallele=2.79E-03, Pgenotype=5.00E-03, OR=1.429) and rs2199503 (Pallele=0.020, Pgenotype= 0.040, OR=1.157) showed association with major depressive disorder before Bonferroni correction. rs6771023 (adjusted Pallele=1.64E-03, adjusted Pgenotype=6.00E-03, OR=0.701) and rs2199503 (adjusted Pallele=0.001, adjusted Pgenotype=0.002, OR=1.251) showed significant association with schizophrenia after Bonferroni correction. rs2199503 (adjusted Pallele=1.70E-03, adjusted Pgenotype=0.006, OR=1.208) remained to be significant in the combined cases of major depressive disorder and schizophrenia after Bonferroni correction. 26186530 2015
dbSNP: rs334535
rs334535
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
CUI: C0041696
Disease:
Unipolar Depression 		0.010 GeneticVariation BEFREE We found rs334535 (Pallele=2.79E-03, Pgenotype=5.00E-03, OR=1.429) and rs2199503 (Pallele=0.020, Pgenotype= 0.040, OR=1.157) showed association with major depressive disorder before Bonferroni correction. rs6771023 (adjusted Pallele=1.64E-03, adjusted Pgenotype=6.00E-03, OR=0.701) and rs2199503 (adjusted Pallele=0.001, adjusted Pgenotype=0.002, OR=1.251) showed significant association with schizophrenia after Bonferroni correction. rs2199503 (adjusted Pallele=1.70E-03, adjusted Pgenotype=0.006, OR=1.208) remained to be significant in the combined cases of major depressive disorder and schizophrenia after Bonferroni correction. 26186530 2015
dbSNP: rs6771023
rs6771023
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
CUI: C0041696
Disease:
Unipolar Depression 		0.010 GeneticVariation BEFREE We found rs334535 (Pallele=2.79E-03, Pgenotype=5.00E-03, OR=1.429) and rs2199503 (Pallele=0.020, Pgenotype= 0.040, OR=1.157) showed association with major depressive disorder before Bonferroni correction. rs6771023 (adjusted Pallele=1.64E-03, adjusted Pgenotype=6.00E-03, OR=0.701) and rs2199503 (adjusted Pallele=0.001, adjusted Pgenotype=0.002, OR=1.251) showed significant association with schizophrenia after Bonferroni correction. rs2199503 (adjusted Pallele=1.70E-03, adjusted Pgenotype=0.006, OR=1.208) remained to be significant in the combined cases of major depressive disorder and schizophrenia after Bonferroni correction. 26186530 2015