LCE1C, late cornified envelope 1C, 353133

N. diseases: 2; N. variants: 1
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6701216
rs6701216
Entrez Id: 353133
Gene Symbol: LCE1C
LCE1C
CUI: C0033860
Disease:
Psoriasis 		0.010 GeneticVariation BEFREE Novel associations replicated in the U.S. PS cohort included the region harboring lipoma HMGIC fusion partner (LHFP) and conserved oligomeric golgi complex component 6 (COG6) genes on chromosome 13q13 (combined P = 2x10(-6) for rs7993214; OR = 0.71), the late cornified envelope gene cluster (LCE) from the Epidermal Differentiation Complex (PSORS4) (combined P = 6.2x10(-5) for rs6701216; OR 1.45) and a region of LD at 15q21 (combined P = 2.9x10(-5) for rs3803369; OR = 1.43). 18369459 2008
dbSNP: rs6701216
rs6701216
Entrez Id: 353133
Gene Symbol: LCE1C
LCE1C
CUI: C1832097
Disease:
EPIDERMAL DIFFERENTIATION COMPLEX 		0.010 GeneticVariation BEFREE Novel associations replicated in the U.S. PS cohort included the region harboring lipoma HMGIC fusion partner (LHFP) and conserved oligomeric golgi complex component 6 (COG6) genes on chromosome 13q13 (combined P = 2x10(-6) for rs7993214; OR = 0.71), the late cornified envelope gene cluster (LCE) from the Epidermal Differentiation Complex (PSORS4) (combined P = 6.2x10(-5) for rs6701216; OR 1.45) and a region of LD at 15q21 (combined P = 2.9x10(-5) for rs3803369; OR = 1.43). 18369459 2008