IL4R, interleukin 4 receptor, 3566

N. diseases: 242; N. variants: 36
Disease: Glioblastoma Multiforme ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1801275
rs1801275
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C1621958
Disease:
Glioblastoma Multiforme 		0.030 GeneticVariation BEFREE By χ(2) test, the rs1801275</span> in IL-4R showed an increased risk of GBM. 23663500 2013
dbSNP: rs1801275
rs1801275
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C1621958
Disease:
Glioblastoma Multiforme 		0.030 GeneticVariation BEFREE To see whether previous Swedish results (110 cases, 430 controls) would be replicated, we estimated the association between glioblastoma and two IL-4Ralpha (rs1805015, rs1801275) and two IL-13 (rs20541, rs1800925) SNPs and their haplotypes and one COX-2 SNP (-765GC) using additional English, Danish, and Finnish data (217 cases, 1,171 controls). 18006935 2007
dbSNP: rs1801275
rs1801275
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C1621958
Disease:
Glioblastoma Multiforme 		0.030 GeneticVariation BEFREE In addition, IL-4RA Ser478Pro TC, CC, and IL-4RA Gln551Arg AG, AA are positively associated with GBM (OR, 1.64; 95% CI, 1.05-2.55; 1.61; 95% CI, 1.05-2.47), whereas IL-13 -1,112 CT, TT is negatively associated with GBM (0.56; 95% CI, 0.33-0.96). 16024651 2005
dbSNP: rs1805015
rs1805015
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C1621958
Disease:
Glioblastoma Multiforme 		0.020 GeneticVariation BEFREE To see whether previous Swedish results (110 cases, 430 controls) would be replicated, we estimated the association between glioblastoma and two IL-4Ralpha (rs1805015, rs1801275) and two IL-13 (rs20541, rs1800925) SNPs and their haplotypes and one COX-2 SNP (-765GC) using additional English, Danish, and Finnish data (217 cases, 1,171 controls). 18006935 2007
dbSNP: rs1805015
rs1805015
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C1621958
Disease:
Glioblastoma Multiforme 		0.020 GeneticVariation BEFREE In addition, IL-4RA Ser478Pro TC, CC, and IL-4RA Gln551Arg AG, AA are positively associated with GBM (OR, 1.64; 95% CI, 1.05-2.55; 1.61; 95% CI, 1.05-2.47), whereas IL-13 -1,112 CT, TT is negatively associated with GBM (0.56; 95% CI, 0.33-0.96). 16024651 2005