NFATC2, nuclear factor of activated T cells 2, 4773

N. diseases: 154; N. variants: 22
Disease: Neoplasms ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs757748401
rs757748401
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE Finally, preclinical experiments suggest that targeting the NFATc2-STAT3-GSK-3β module inhibits proliferation and tumor growth and interferes with inflammation-induced pancreatic cancer progression in Kras(G12D) mice. 26823495 2016
dbSNP: rs6021191
rs6021191
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE RNA-seq data available from 65 SJCRH ALL tumor samples and 52 Yoruba HapMap samples showed that samples carrying the rs6021191 variant had higher NFATC2 expression compared with noncarriers (P = 1.1 × 10(-3) and 0.03, respectively). 25987655 2015