DisGeNET - a database of gene-disease associations

ST3GAL4, ST3 beta-galactoside alpha-2,3-sialyltransferase 4, 6484

N. diseases: 115; N. variants: 26

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs11220462

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.800

GeneticVariation

GWASCAT

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.

30926973

2019

dbSNP:

rs11220462

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.800

GeneticVariation

GWASCAT

A large electronic-health-record-based genome-wide study of serum lipids.

29507422

2018

dbSNP:

rs11220462

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.800

GeneticVariation

GWASCAT

A large electronic-health-record-based genome-wide study of serum lipids.

29507422

2018

dbSNP:

rs11220462

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.800

GeneticVariation

GWASCAT

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

28334899

2017

dbSNP:

rs11220462

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.800

GeneticVariation

GWASCAT

Discovery and refinement of loci associated with lipid levels.

24097068

2013

dbSNP:

rs11220462

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.800

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

dbSNP:

rs11220462

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.800

GeneticVariation

GWASCAT

Discovery and refinement of loci associated with lipid levels.

24097068

2013

dbSNP:

rs11220462

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.800

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

dbSNP:

rs2236653

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C0201850
Disease:

Alkaline phosphatase measurement

0.800

GeneticVariation

GWASCAT

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.

22001757

2011

dbSNP:

rs2236653

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C0201850
Disease:

Alkaline phosphatase measurement

0.800

GeneticVariation

GWASDB

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.

22001757

2011

dbSNP:

rs11220462

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.800

GeneticVariation

GWASCAT

Biological, clinical and population relevance of 95 loci for blood lipids.

20686565

2010

dbSNP:

rs11220462

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C1445957
Disease:

Serum total cholesterol measurement

0.800

GeneticVariation

GWASDB

Biological, clinical and population relevance of 95 loci for blood lipids.

20686565

2010

dbSNP:

rs11220462

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.800

GeneticVariation

GWASCAT

Biological, clinical and population relevance of 95 loci for blood lipids.

20686565

2010

dbSNP:

rs11220462

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.800

GeneticVariation

GWASDB

Biological, clinical and population relevance of 95 loci for blood lipids.

20686565

2010

dbSNP:

rs4935969

Entrez Id:	6484;84623
Gene Symbol:	ST3GAL4;KIRREL3

ST3GAL4;KIRREL3

CUI:	C0018498
Disease:

Hair Color

0.800

GeneticVariation

GWASCAT

Web-based, participant-driven studies yield novel genetic associations for common traits.

20585627

2010

dbSNP:

rs4935969

Entrez Id:	6484;84623
Gene Symbol:	ST3GAL4;KIRREL3

ST3GAL4;KIRREL3

CUI:	C0018498
Disease:

Hair Color

0.800

GeneticVariation

GWASDB

Web-based, participant-driven studies yield novel genetic associations for common traits.

20585627

2010

dbSNP:

rs11220465

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C0005890
Disease:

Body Height

0.700

GeneticVariation

GWASCAT

Characterizing rare and low-frequency height-associated variants in the Japanese population.

31562340

2019

dbSNP:

rs11220471

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C4722217
Disease:

E-selectin Measurement

0.700

GeneticVariation

GWASCAT

Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns.

31217265

2019

dbSNP:

rs142029184

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C1861172
Disease:

Venous Thromboembolism

0.700

GeneticVariation

GWASCAT

Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism.

31420334

2019

dbSNP:

rs35458154

Entrez Id:	6484;84623
Gene Symbol:	ST3GAL4;KIRREL3

ST3GAL4;KIRREL3

CUI:	C2825857
Disease:

Factor VIII measurement

0.700

GeneticVariation

GWASCAT

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.

30586737

2019

dbSNP:

rs35458154

Entrez Id:	6484;84623
Gene Symbol:	ST3GAL4;KIRREL3

ST3GAL4;KIRREL3

CUI:	C2239219
Disease:

von Willebrand's factor (lab test)

0.700

GeneticVariation

GWASCAT

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.

30586737

2019

dbSNP:

rs66619583

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C1261502
Disease:

Finding of Mean Corpuscular Hemoglobin

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs76970536

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C0001948
Disease:

Alcohol consumption

0.700

GeneticVariation

GWASCAT

Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.

30698716

2019

dbSNP:

rs76970536

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C0392885
Disease:

High density lipoprotein measurement

0.700

GeneticVariation

GWASCAT

Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.

30698716

2019

dbSNP:

rs76970536

Entrez Id:	6484
Gene Symbol:	ST3GAL4

ST3GAL4

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.700

GeneticVariation

GWASCAT

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.

30670697

2019