SUMO2, small ubiquitin like modifier 2, 6613

N. diseases: 42; N. variants: 3
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs35271045
rs35271045
Entrez Id: 6613
Gene Symbol: SUMO2
SUMO2
CUI: C1278049
Disease:
Serum gamma-glutamyl transferase measurement 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs35271045
rs35271045
Entrez Id: 6613
Gene Symbol: SUMO2
SUMO2
CUI: C0002395
Disease:
Alzheimer's Disease 		0.010 GeneticVariation BEFREE In addition, two polymorphisms of SUMO2 were significantly associated with an increased risk of AD in female group (the GA genotype of rs35271045: adjusted OR=2.879, 95% CI=1.399-5.924, p-value=0.004; and the TC genotype of rs9913676: adjusted OR=2.460, 95% CI=1.197-5.057, p-value=0.014). 27084229 2016
dbSNP: rs9913676
rs9913676
Entrez Id: 6613
Gene Symbol: SUMO2
SUMO2
CUI: C0002395
Disease:
Alzheimer's Disease 		0.010 GeneticVariation BEFREE In addition, two polymorphisms of SUMO2 were significantly associated with an increased risk of AD in female group (the GA genotype of rs35271045: adjusted OR=2.879, 95% CI=1.399-5.924, p-value=0.004; and the TC genotype of rs9913676: adjusted OR=2.460, 95% CI=1.197-5.057, p-value=0.014). 27084229 2016
dbSNP: rs760160309
rs760160309
Entrez Id: 6613
Gene Symbol: SUMO2
SUMO2
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.010 GeneticVariation BEFREE A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus. 15123604 2004