TPH1, tryptophan hydroxylase 1, 7166

N. diseases: 127; N. variants: 11
Disease: Diarrhea ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs211105
rs211105
Entrez Id: 7166
Gene Symbol: TPH1
TPH1
CUI: C0011991
Disease:
Diarrhea 		0.020 GeneticVariation BEFREE Only the group of patients with diarrhea-predominant irritable bowel syndrome showed a significant correlation between the TPH1 rs211105 T/T genotype and lower scores for role physical and mental health, and higher scores for indigestion and diarrhea. 29892168 2018
dbSNP: rs211105
rs211105
Entrez Id: 7166
Gene Symbol: TPH1
TPH1
CUI: C0011991
Disease:
Diarrhea 		0.020 GeneticVariation BEFREE The mean scores of diarrhea at baseline were significantly higher (5.2 vs 3.7, p = 0.005) in patients with TPH1 rs211105 T/T than those with the G allele. 25428414 2015