|
Glomerular Filtration Rate
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
|
26831199 |
2016 |
|
Glomerular Filtration Rate
|
|
0.800 |
GeneticVariation
|
GWASDB |
Using multiple measures for quantitative trait association analyses: application to estimated glomerular filtration rate.
|
23535967 |
2013 |
|
Chronic Kidney Diseases
|
|
0.730 |
GeneticVariation
|
BEFREE |
The genetic rs12917707-G>T variant in uromodulin (UMOD) has been associated with renal function, chronic kidney disease and hypertension with the minor T-allele showing a protective effect.
|
28418009 |
2018 |
|
Chronic Kidney Diseases
|
|
0.730 |
GeneticVariation
|
BEFREE |
The rs12917707 was not associated with CKD.
|
28954491 |
2017 |
|
Chronic Kidney Diseases
|
|
0.730 |
GeneticVariation
|
BEFREE |
In recent genetic association studies, common variants including rs12917707 in the UMOD locus have shown strong evidence of association with eGFR, prevalent and incident chronic kidney disease and uromodulin urinary concentration in general population cohorts.
|
22947327 |
2012 |
|
Chronic Kidney Diseases
|
|
0.730 |
GeneticVariation
|
GWASDB |
Genome-wide association and functional follow-up reveals new loci for kidney function.
|
22479191 |
2012 |
|
Chronic Kidney Diseases
|
|
0.730 |
GeneticVariation
|
GWASDB |
New loci associated with kidney function and chronic kidney disease.
|
20383146 |
2010 |
|
Kidney Failure, Chronic
|
|
0.720 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of kidney function decline in individuals of European descent.
|
25493955 |
2015 |
|
Kidney Failure, Chronic
|
|
0.720 |
GeneticVariation
|
BEFREE |
We tested a large cohort of Caucasian patients for association of rs12917707 with IgA nephropathy showing a benign, stable course and with IgA nephropathy that progressed toward end stage renal failure.
|
25163389 |
2014 |
|
Kidney Failure, Chronic
|
|
0.720 |
GeneticVariation
|
BEFREE |
The rs12917707 minor allele showed association with lower risk of ESRD (OR 0.89 [0.76-1.03], p = 0.04) consistent in effect size and direction with the previous report (Böger et al, PLoS Genet 2011).
|
22947327 |
2012 |
|
Kidney Failure, Chronic
|
|
0.720 |
GeneticVariation
|
GWASCAT |
New loci associated with kidney function and chronic kidney disease.
|
20383146 |
2010 |
|
Kidney Failure, Chronic
|
|
0.720 |
GeneticVariation
|
GWASCAT |
Multiple loci associated with indices of renal function and chronic kidney disease.
|
19430482 |
2009 |
|
Diabetes
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
|
26831199 |
2016 |
|
Creatinine measurement, serum (procedure)
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
|
26831199 |
2016 |
|
Diabetes Mellitus
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
|
26831199 |
2016 |
|
Creatinine measurement, serum (procedure)
|
|
0.700 |
GeneticVariation
|
GWASCAT |
New loci associated with kidney function and chronic kidney disease.
|
20383146 |
2010 |
|
Hypertensive disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
The genetic rs12917707-G>T variant in uromodulin (UMOD) has been associated with renal function, chronic kidney disease and hypertension with the minor T-allele showing a protective effect.
|
28418009 |
2018 |
|
Hypertensive disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
We investigated the associations between an important single nucleotide polymorphism (SNP) in UMOD, that is rs12917707-G>T, and estimated glomerular filtration rate (eGFR), BP and cardiac organ damage as determined by echocardiography in patients with arterial hypertension.
|
28598953 |
2017 |
|
Chronic kidney disease stage 5
|
|
0.020 |
GeneticVariation
|
BEFREE |
We tested a large cohort of Caucasian patients for association of rs12917707 with IgA nephropathy showing a benign, stable course and with IgA nephropathy that progressed toward end stage renal failure.
|
25163389 |
2014 |
|
Chronic kidney disease stage 5
|
|
0.020 |
GeneticVariation
|
BEFREE |
The rs12917707 minor allele showed association with lower risk of ESRD (OR 0.89 [0.76-1.03], p = 0.04) consistent in effect size and direction with the previous report (Böger et al, PLoS Genet 2011).
|
22947327 |
2012 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.010 |
GeneticVariation
|
BEFREE |
The rs12917707 polymorphism at the UMOD locus and glomerular filtration rate in individuals with type 2 diabetes: evidence of heterogeneity across two different European populations.
|
27448670 |
2017 |
|
Kidney Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
The common rs12917707 polymorphism previously linked to renal function and kidney disease was not associated with impaired filtration rate in our cohort.
|
26040415 |
2015 |
|
IGA Glomerulonephritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
We tested a large cohort of Caucasian patients for association of rs12917707 with IgA nephropathy showing a benign, stable course and with IgA nephropathy that progressed toward end stage renal failure.
|
25163389 |
2014 |