rs1837253, None

N. diseases: 10
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474 2019
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASCAT Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study. 30552067 2019
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation BEFREE rs1837253 is associated with asthma susceptibility and may increase the risk of asthma in Zhuang people in Guangxi. 31066119 2019
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASCAT A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. 29785011 2018
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASCAT Identification of Four Novel Loci in Asthma in European American and African American Populations. 27611488 2017
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation BEFREE Surprisingly, rs1837253 (consistently associated with asthma) showed no correlation with TSLP expression levels. 26119467 2015
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation BEFREE Recent candidate gene and genome-wide association studies have identified "protective" associations between the single-nucleotide polymorphism (SNP) rs1837253 in the TSLP gene and risk for allergy, asthma, and airway hyperresponsiveness. 25515628 2015
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549 2011
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549 2011
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASDB Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. 21804548 2011
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. 21804548 2011
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation BEFREE Two SNPs in TSLP (rs1837253 and rs2289276) were significantly associated with a reduced risk of asthma in combined analyses of all cohorts (P values of 2 × 10(-5) and 1 × 10(-5) , respectively). 20560908 2010
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASDB A large-scale, consortium-based genomewide association study of asthma. 20860503 2010
Allergic Reaction
CUI: C1527304
Disease: Allergic Reaction
0.800 GeneticVariation GWASCAT A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. 29785011 2018
Allergic Reaction
CUI: C1527304
Disease: Allergic Reaction
0.800 GeneticVariation GWASCAT Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. 29083406 2017
Allergic Reaction
CUI: C1527304
Disease: Allergic Reaction
0.800 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
Nasal Polyps
CUI: C0027430
Disease: Nasal Polyps
0.700 GeneticVariation GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019
Adult onset asthma
CUI: C0741260
Disease: Adult onset asthma
0.700 GeneticVariation GWASCAT Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies. 31036433 2019
Adult onset asthma
CUI: C0741260
Disease: Adult onset asthma
0.700 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
Respiratory Tract Diseases
CUI: C0035242
Disease: Respiratory Tract Diseases
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
Childhood asthma
CUI: C0264408
Disease: Childhood asthma
0.700 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
Childhood asthma
CUI: C0264408
Disease: Childhood asthma
0.700 GeneticVariation GWASCAT Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies. 31036433 2019