rs189037, ATM;NPAT

N. diseases: 22
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.060 GeneticVariation BEFREE Our findings highlight that <i>ATM</i> rs189037 significantly increases cancer susceptibility in non-smokers, rather than in smokers.The association is prominent in LC. 31201228 2019
Primary malignant neoplasm of lung
CUI: C1306460
Disease: Primary malignant neoplasm of lung
0.060 GeneticVariation BEFREE Results of this meta-analysis suggest that rs189037 is associated with the occurrence of lung cancer, breast cancer, and oral cancer as the risk factor. 30709340 2019
Primary malignant neoplasm of lung
CUI: C1306460
Disease: Primary malignant neoplasm of lung
0.060 GeneticVariation BEFREE Our findings highlight that <i>ATM</i> rs189037 significantly increases cancer susceptibility in non-smokers, rather than in smokers.The association is prominent in LC. 31201228 2019
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.060 GeneticVariation BEFREE Results of this meta-analysis suggest that rs189037 is associated with the occurrence of lung cancer, breast cancer, and oral cancer as the risk factor. 30709340 2019
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.060 GeneticVariation BEFREE Our findings highlight that <i>ATM</i> rs189037 significantly increases cancer susceptibility in non-smokers, rather than in smokers.The association is prominent in LC. 31201228 2019
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.060 GeneticVariation BEFREE Results of this meta-analysis suggest that rs189037 is associated with the occurrence of lung cancer, breast cancer, and oral cancer as the risk factor. 30709340 2019
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.060 GeneticVariation BEFREE The results indicate that the ATM rs189037, rs664677 and rs664143 gene polymorphisms are risk factors for lung cancer, while the ATM rs189037 variant was significantly associated with RP risk. 29246212 2017
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.060 GeneticVariation BEFREE The results indicate that the ATM rs189037, rs664677 and rs664143 gene polymorphisms are risk factors for lung cancer, while the ATM rs189037 variant was significantly associated with RP risk. 29246212 2017
Primary malignant neoplasm of lung
CUI: C1306460
Disease: Primary malignant neoplasm of lung
0.060 GeneticVariation BEFREE The results indicate that the ATM rs189037, rs664677 and rs664143 gene polymorphisms are risk factors for lung cancer, while the ATM rs189037 variant was significantly associated with RP risk. 29246212 2017
Primary malignant neoplasm of lung
CUI: C1306460
Disease: Primary malignant neoplasm of lung
0.060 GeneticVariation BEFREE This study suggested that rs189037 (G>A) polymorphism is associated with lung cancer risk in Chinese Han population. 25541996 2014
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.060 GeneticVariation BEFREE This study suggested that rs189037 (G>A) polymorphism is associated with lung cancer risk in Chinese Han population. 25541996 2014
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.060 GeneticVariation BEFREE This study suggested that rs189037 (G>A) polymorphism is associated with lung cancer risk in Chinese Han population. 25541996 2014
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.060 GeneticVariation BEFREE In this hospital-based matched case-control study, associations of up to seven ATM single nucleotide polymorphisms (rs600931, rs652311, rs227060, rs228589, rs227092, rs624366 and rs189037) with lung cancer risk were investigated among Taiwanese. 24023351 2013
Primary malignant neoplasm of lung
CUI: C1306460
Disease: Primary malignant neoplasm of lung
0.060 GeneticVariation BEFREE In this hospital-based matched case-control study, associations of up to seven ATM single nucleotide polymorphisms (rs600931, rs652311, rs227060, rs228589, rs227092, rs624366 and rs189037) with lung cancer risk were investigated among Taiwanese. 24023351 2013
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.060 GeneticVariation BEFREE In this hospital-based matched case-control study, associations of up to seven ATM single nucleotide polymorphisms (rs600931, rs652311, rs227060, rs228589, rs227092, rs624366 and rs189037) with lung cancer risk were investigated among Taiwanese. 24023351 2013
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.060 GeneticVariation BEFREE SNPs associated with lung cancer prognosis primarily mapped to 14 genes in different repair pathways, and 6 SNPs were remained in the final model after multivariate stepwise Cox regression analysis: ATM rs189037; MRE11A rs11020802; ERCC2 rs1799793; MBD4 rs140693; XRCC1 rs25487, and PMS1 rs5742933. 21739480 2012
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.060 GeneticVariation BEFREE SNPs associated with lung cancer prognosis primarily mapped to 14 genes in different repair pathways, and 6 SNPs were remained in the final model after multivariate stepwise Cox regression analysis: ATM rs189037; MRE11A rs11020802; ERCC2 rs1799793; MBD4 rs140693; XRCC1 rs25487, and PMS1 rs5742933. 21739480 2012
Primary malignant neoplasm of lung
CUI: C1306460
Disease: Primary malignant neoplasm of lung
0.060 GeneticVariation BEFREE SNPs associated with lung cancer prognosis primarily mapped to 14 genes in different repair pathways, and 6 SNPs were remained in the final model after multivariate stepwise Cox regression analysis: ATM rs189037; MRE11A rs11020802; ERCC2 rs1799793; MBD4 rs140693; XRCC1 rs25487, and PMS1 rs5742933. 21739480 2012
Malignant Neoplasms
CUI: C0006826
Disease: Malignant Neoplasms
0.020 GeneticVariation BEFREE Summary results indicated that an association was found between rs189037 and cancer risk. 30709340 2019
Primary malignant neoplasm
CUI: C1306459
Disease: Primary malignant neoplasm
0.020 GeneticVariation BEFREE Summary results indicated that an association was found between rs189037 and cancer risk. 30709340 2019
Malignant neoplasm of mouth
CUI: C0153381
Disease: Malignant neoplasm of mouth
0.020 GeneticVariation BEFREE Results of this meta-analysis suggest that rs189037 is associated with the occurrence of lung cancer, breast cancer, and oral cancer as the risk factor. 30709340 2019
Malignant Neoplasms
CUI: C0006826
Disease: Malignant Neoplasms
0.020 GeneticVariation BEFREE Results indicated a significant association of <i>ATM</i> rs189037 with cancer risk. 31201228 2019
Primary malignant neoplasm
CUI: C1306459
Disease: Primary malignant neoplasm
0.020 GeneticVariation BEFREE Results indicated a significant association of <i>ATM</i> rs189037 with cancer risk. 31201228 2019
Lip and Oral Cavity Carcinoma
CUI: C0220641
Disease: Lip and Oral Cavity Carcinoma
0.020 GeneticVariation BEFREE Results of this meta-analysis suggest that rs189037 is associated with the occurrence of lung cancer, breast cancer, and oral cancer as the risk factor. 30709340 2019
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.020 GeneticVariation BEFREE The association of single nucleotide polymorphism rs189037C>T in ATM gene with coronary artery disease in Chinese Han populations: A case control study. 29369221 2018