|
Multiple Sclerosis
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
|
22190364 |
2011 |
|
Multiple Sclerosis
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
|
22190364 |
2011 |
|
Ulcerative Colitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
While rs2293152</span> (GC) was protective, rs2293152 (CC) increased the susceptibility to ulcerative colitis (p=0.009, p=0.001).
|
27852544 |
2016 |
|
Liver carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
However, no significant association between rs2293152 and HCC development was observed.
|
26745093 |
2015 |
|
Behcet Syndrome
|
|
0.020 |
GeneticVariation
|
BEFREE |
In the genotype-based analysis, the JAK1 rs310245 TT homozygote (1.79 [1.14-2.82], p=0.012) and the STAT3 rs2293152 GG homozygote (2.01 [1.16-3.47], p=0.011) showed associations with BD.
|
24428981 |
2014 |
|
Ulcerative Colitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our study implies that the STAT3 rs2293152</span> polymorphism may be associated with the occurrence of UC and might be used as a predictive factor for UC in the Chinese Han population.
|
24781989 |
2014 |
|
Liver carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
In multivariate regression analyses, multiplicative interaction of rs1053004 with T1674C/G significantly increased HCC risk, whereas rs2293152 and A1726C interaction reduced it, adjusting for covariates including HBV mutations in the enhancer II/basal core promoter/precore region; the interaction of rs4796793 with preS2 start codon mutation significantly increased HCC risk, adjusting for covariates including HBV mutations in the preS region.
|
23386590 |
2013 |
|
Behcet Syndrome
|
|
0.020 |
GeneticVariation
|
BEFREE |
A significantly increased frequency of the GG genotype of the STAT3 rs2293152 was observed in patients with BD (Bonferroni-corrected P value = 0.021).
|
22205606 |
2012 |
|
Experimental Organism Basal Cell Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The presence of C allele in STAT3 rs2293152 polymorphism was associated with increased risk of BCC (aOR 1.31; 95% CI 1.01-1.69; p = 0.04).
|
31342143 |
2019 |
|
Carcinoma, Basal Cell
|
|
0.010 |
GeneticVariation
|
BEFREE |
The presence of C allele in STAT3 rs2293152 polymorphism was associated with increased risk of BCC (aOR 1.31; 95% CI 1.01-1.69; p = 0.04).
|
31342143 |
2019 |
|
Crohn Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Additionally, rs10758669 and rs2293152 in Crohn's disease and rs8074524, rs3816769, and rs10758669 in ulcerative colitis were associated with the requirement of immunsuppression.
|
27852544 |
2016 |
|
Complete atrioventricular block
|
|
0.010 |
GeneticVariation
|
BEFREE |
Recent studies demonstrated that single nucleotide polymorphisms (SNPs) rs2293152 in signal transducer and activator of transcription 3 (STAT3) and rs7574865 in signal transducer and activator of transcription 4 (STAT4) are associated with chronic hepatitis B (CHB)-related HCC in the Chinese population.
|
26745093 |
2015 |
|
Hepatitis B, Chronic
|
|
0.010 |
GeneticVariation
|
BEFREE |
Recent studies demonstrated that single nucleotide polymorphisms (SNPs) rs2293152 in signal transducer and activator of transcription 3 (STAT3) and rs7574865 in signal transducer and activator of transcription 4 (STAT4) are associated with chronic hepatitis B (CHB)-related HCC in the Chinese population.
|
26745093 |
2015 |
|
Ankylosing spondylitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
SNPs in TNFRSF1A (rs4149577, p = 8.2 × 10⁻⁴), STAT3 (rs2293152, p = 0.0015; rs1053005, p = 0.017) and ERAP1 (rs27038, p = 0.0091; rs27037, p = 0.0092) were significantly associated with AS in Han Chinese.
|
21068102 |
2011 |