|
Adenocarcinoma of lung (disorder)
|
|
0.810 |
GeneticVariation
|
BEFREE |
Our data suggest that Snail1 may be a co-factor of rs2853677 for predicting lung adenocarcinoma susceptibility and prognosis.
|
27191258 |
2016 |
|
Adenocarcinoma of lung (disorder)
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population.
|
27393504 |
2016 |
|
Adenocarcinoma of lung (disorder)
|
|
0.810 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
|
22797724 |
2012 |
|
Adenocarcinoma of lung (disorder)
|
|
0.810 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
|
22797724 |
2012 |
|
Carcinoma of lung
|
|
0.740 |
GeneticVariation
|
BEFREE |
Four polymorphisms exhibited prominent associations with lung cancer risk, including rs7726159 (OR = 1.34, 95%CI: 1.18-1.52, P = 7.78 × 10<sup>-6</sup> ), rs10054203 (OR = 1.29, 95%CI: 1.13-1.46, P = 1.37 × 10<sup>-4</sup> ), rs2736107 (OR = 1.28, 95%CI: 1.11-1.47, P = 5.14 × 10<sup>-4</sup> ), and rs2853677 (OR = 1.23, 95%CI: 1.08-1.39, P = 0.002).
|
30680798 |
2019 |
|
Carcinoma of lung
|
|
0.740 |
GeneticVariation
|
BEFREE |
We observed that variant rs2853677 was strongly associated with lung cancer and leukemia risk with an odds ratio (OR) =1.8 (1.03-3.2 at 95% CI); p value (adjusted) = 0.03; odds ratio (OR) =2.9 (1.4-5.5.at 95% CI); p value (adjusted) = 0.002, respectively.
|
31126249 |
2019 |
|
Carcinoma of lung
|
|
0.740 |
GeneticVariation
|
BEFREE |
Our study indicated that rs10936599 (<i>TERC</i>) and rs10069690, rs2242652 and rs2853677 in <i>TERT</i> and haplotype "TA" of <i>TERT</i> were revealed as risk factors of lung cancer in a Chinese Han population.
|
29299136 |
2017 |
|
Carcinoma of lung
|
|
0.740 |
GeneticVariation
|
BEFREE |
The association with rs2853677 is driven by the adenocarcinoma subtype of lung cancer (p=1.3×10(-8); OR=1.37; 95% CI=1.23-1.54).
|
27393504 |
2016 |
|
Carcinoma of lung
|
|
0.740 |
GeneticVariation
|
GWASCAT |
The association with rs2853677 is driven by the adenocarcinoma subtype of lung cancer (p=1.3×10(-8); OR=1.37; 95% CI=1.23-1.54).
|
27393504 |
2016 |
|
Benign Prostatic Hyperplasia
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA.
|
30410027 |
2018 |
|
Lower Urinary Tract Symptoms
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA.
|
30410027 |
2018 |
|
Prostate specific antigen measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA.
|
30410027 |
2018 |
|
Mean Corpuscular Volume (result)
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
Primary malignant neoplasm of lung
|
|
0.040 |
GeneticVariation
|
BEFREE |
We observed that variant rs2853677 was strongly associated with lung cancer and leukemia risk with an odds ratio (OR) =1.8 (1.03-3.2 at 95% CI); p value (adjusted) = 0.03; odds ratio (OR) =2.9 (1.4-5.5.at 95% CI); p value (adjusted) = 0.002, respectively.
|
31126249 |
2019 |
|
Malignant neoplasm of lung
|
|
0.040 |
GeneticVariation
|
BEFREE |
Four polymorphisms exhibited prominent associations with lung cancer risk, including rs7726159 (OR = 1.34, 95%CI: 1.18-1.52, P = 7.78 × 10<sup>-6</sup> ), rs10054203 (OR = 1.29, 95%CI: 1.13-1.46, P = 1.37 × 10<sup>-4</sup> ), rs2736107 (OR = 1.28, 95%CI: 1.11-1.47, P = 5.14 × 10<sup>-4</sup> ), and rs2853677 (OR = 1.23, 95%CI: 1.08-1.39, P = 0.002).
|
30680798 |
2019 |
|
Malignant neoplasm of lung
|
|
0.040 |
GeneticVariation
|
BEFREE |
We observed that variant rs2853677 was strongly associated with lung cancer and leukemia risk with an odds ratio (OR) =1.8 (1.03-3.2 at 95% CI); p value (adjusted) = 0.03; odds ratio (OR) =2.9 (1.4-5.5.at 95% CI); p value (adjusted) = 0.002, respectively.
|
31126249 |
2019 |
|
Primary malignant neoplasm of lung
|
|
0.040 |
GeneticVariation
|
BEFREE |
Four polymorphisms exhibited prominent associations with lung cancer risk, including rs7726159 (OR = 1.34, 95%CI: 1.18-1.52, P = 7.78 × 10<sup>-6</sup> ), rs10054203 (OR = 1.29, 95%CI: 1.13-1.46, P = 1.37 × 10<sup>-4</sup> ), rs2736107 (OR = 1.28, 95%CI: 1.11-1.47, P = 5.14 × 10<sup>-4</sup> ), and rs2853677 (OR = 1.23, 95%CI: 1.08-1.39, P = 0.002).
|
30680798 |
2019 |
|
Malignant neoplasm of lung
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our study indicated that rs10936599 (<i>TERC</i>) and rs10069690, rs2242652 and rs2853677 in <i>TERT</i> and haplotype "TA" of <i>TERT</i> were revealed as risk factors of lung cancer in a Chinese Han population.
|
29299136 |
2017 |
|
Primary malignant neoplasm of lung
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our study indicated that rs10936599 (<i>TERC</i>) and rs10069690, rs2242652 and rs2853677 in <i>TERT</i> and haplotype "TA" of <i>TERT</i> were revealed as risk factors of lung cancer in a Chinese Han population.
|
29299136 |
2017 |
|
Primary malignant neoplasm of lung
|
|
0.040 |
GeneticVariation
|
BEFREE |
The association with rs2853677 is driven by the adenocarcinoma subtype of lung cancer (p=1.3×10(-8); OR=1.37; 95% CI=1.23-1.54).
|
27393504 |
2016 |
|
Malignant neoplasm of lung
|
|
0.040 |
GeneticVariation
|
BEFREE |
The association with rs2853677 is driven by the adenocarcinoma subtype of lung cancer (p=1.3×10(-8); OR=1.37; 95% CI=1.23-1.54).
|
27393504 |
2016 |
|
Non-Small Cell Lung Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
The results of this study suggested that rs2853677 of TERT signifies association in multiple cancers and suggests that it can become potential marker for diagnosis of non-small cell lung cancer and leukemia.
|
31126249 |
2019 |
|
Breast Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
In addition, individuals with the AA genotype of rs2853677 have longer telomeres than those of breast cancer patients with the AG genotype (<i>p</i>=0.011).
|
30607160 |
2018 |
|
Non-Small Cell Lung Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our results indicated that rs2853677 and rs2853691 in the <i>TERT</i> gene might be associated with NSCLC in this Chinese Han population.
|
29928145 |
2018 |
|
Malignant neoplasm of breast
|
|
0.020 |
GeneticVariation
|
BEFREE |
In addition, individuals with the AA genotype of rs2853677 have longer telomeres than those of breast cancer patients with the AG genotype (<i>p</i>=0.011).
|
30607160 |
2018 |