|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
|
19060911 |
2009 |
|
Serum total cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
High density lipoprotein measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
Serum total cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
High density lipoprotein measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Serum total cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
|
30275531 |
2018 |
|
HYPERTRIGLYCERIDEMIA, SUSCEPTIBILITY TO
|
|
0.700 |
SusceptibilityMutation
|
CLINVAR |
|
|
|
|
Metabolic Syndrome X
|
|
0.070 |
GeneticVariation
|
BEFREE |
In this study, we aimed to determine the association of single nucleotide polymorphisms including: rs662799, rs3135506 and rs2075291 in the apolipoprotein A-V (APOA5) gene in relation to MetS component like triglyceride and HDL-C level in Tehran Lipid and Glucose Study (TLGS).
|
26702748 |
2016 |
|
Metabolic Syndrome X
|
|
0.070 |
GeneticVariation
|
BEFREE |
Two common variants of ApoA5 (namely -1131T>C in the promoter region and c.56C>G in the coding region) with the risk of MetS were analyzed.
|
22905904 |
2012 |
|
Metabolic Syndrome X
|
|
0.070 |
GeneticVariation
|
BEFREE |
The minor allele of rs9939609 (FTO), rs7903146 (TCF7L2), C56G (APOA5), T1131C (APOA5), C482T (APOC3), C455T (APOC3) and 174G>C (IL6) were more prevalent in subjects with MetS, whereas the minor allele of Taq-1B (CETP) was less prevalent in subjects with the MetS.
|
21749608 |
2011 |
|
Metabolic Syndrome X
|
|
0.070 |
GeneticVariation
|
BEFREE |
Here we determined four haplotype-tagging polymorphisms (T-1131C, IVS3+G476A, T1259C, and C56G), and studied the distribution of the naturally occurring major haplotype profiles in MS.
|
19692219 |
2010 |
|
Metabolic Syndrome X
|
|
0.070 |
GeneticVariation
|
BEFREE |
APOA5 -1131T > C and S19W single nucleotide polymorphisms (SNP) have been consistently associated with plasma lipid concentration and metabolic syndrome (MetS), alone and in modulation by dietary factors.
|
19828688 |
2009 |
|
Metabolic Syndrome X
|
|
0.070 |
GeneticVariation
|
BEFREE |
Gender-modulated impact of apolipoprotein A5 gene (APOA5) -1131T>C and c.56C>G polymorphisms on lipids, dyslipidemia and metabolic syndrome in Turkish adults.
|
18601598 |
2008 |
|
Metabolic Syndrome X
|
|
0.070 |
GeneticVariation
|
BEFREE |
Furthermore, the data suggest a different mechanism of APOA5 impact on MetS in Caucasians, as variant c.56C>G (not analyzed in the Japanese study) and not -1131T>C, as in the Japanese subjects, was associated with MetS.
|
17768309 |
2007 |
|
Obesity
|
|
0.060 |
GeneticVariation
|
BEFREE |
Association analysis of APOA5 rs662799 and rs3135506 polymorphisms with obesity in Moroccan patients.
|
26524954 |
2015 |
|
Obesity
|
|
0.060 |
GeneticVariation
|
BEFREE |
The objective of this study was to analyze the interaction of a high fat diet with the APOA2 (rs3813627 and rs5082), APOA5 (rs662799 and rs3135506) and LEPR (rs8179183 and rs1137101) polymorphisms and its relationship with obesity and dyslipidemia in young subjects.
|
26365669 |
2015 |
|
Obesity
|
|
0.060 |
GeneticVariation
|
BEFREE |
In current study two SNPs rs662799 risk allele G (P = 0.03) and rs3135506 risk allele C (P = 0.05) of APOA5 were found to be associated with significant higher risk of triglyceride levels, irrespective of age, sex, obesity, diabetes, hypertension and smoking.
|
24402875 |
2014 |
|
Obesity
|
|
0.060 |
GeneticVariation
|
BEFREE |
In summary, we identified significant interactions for APOA5 S19W and LPL m107 for obesity in Caribbean Hispanics.
|
19629056 |
2010 |
|
Obesity
|
|
0.060 |
GeneticVariation
|
BEFREE |
We found that: (i) genotypes, including those of APOA5 S19W, APOA5 -1131T > C, APOE, GCKR, TRIB1 and TBL2/MLXIPL, were significantly associated with severe HTG; (ii) odds ratios for these genetic variables were significant in both univariate and multivariate regression analyses, irrespective of the presence or absence of diabetes or obesity; (iii) a significant fraction-about one-quarter-of the explained variation in disease status was associated with these genotypes.
|
18596051 |
2008 |
|
Obesity
|
|
0.060 |
GeneticVariation
|
BEFREE |
Specifically, we have examined the interaction between the APOA5-1131T>C and 56C>G (S19W) polymorphisms and the macronutrient intake (total fat, carbohydrate, and protein) in their relation to the body mass index (BMI) and obesity risk in 1,073 men and 1,207 women participating in the Framingham Offspring Study.
|
17211608 |
2007 |
|
Coronary Artery Disease
|
|
0.050 |
GeneticVariation
|
BEFREE |
Mediation analysis yielded a mediation effect of p.S19W on risk of premature CAD through HDL-C (OR = 0.98, P = 0.040) and TG (OR = 0.98, P = 0.042), suggesting a causal relationship between p.S19W and premature CAD partially through its effects on HDL-C and TG levels.
|
30024021 |
2018 |
|
Coronary Artery Disease
|
|
0.050 |
GeneticVariation
|
BEFREE |
The genetic variants of rs3135506 (G), rs10455872 (A) and rs3798220 (G) have low frequency in our population and reflected no association with CAD.
|
29309886 |
2018 |